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相关机构：四川大学中国人民解放军中国环境科学研究院中国科学院生态环境研究中心更多>>
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Mitochondria-derived vesicles:New players in the game of neurodegeneration
《Neural Regeneration Research》2026年第2期679-680,共2页Laura Palumbo Domenico Nuzzo Antonella Girgenti Pasquale Picone 
supported by project Emerging Infectious Diseases One Health Basic and Translational Research Actions addressing Unmet Needs on Emerging Infectious Diseases,INF-ACT,Spoke 1 and Spoke 5,Project number PE00000007,CUP B53C20040570005(to PP and DN).
Introduction:One of the main events that regulate a cell’s well-being is cell-to-cell communication.This intercellular mechanism of information transfer is often mediated by vesicular trafficking.Mitochondrial-derive...
关键词：extracellular vesicles cell cell communication vesicular traffickingmitochondrial derived NEURODEGENERATION mitochondria derived vesicles vesicular trafficking extracellular vesicle ev first 
Exosomes in stroke management:A promising paradigm shift in stroke therapy
《Neural Regeneration Research》2026年第1期6-22,共17页Bo Wang Pinzhen Chen Wenyan Li Zhi Chen 
supported by the Natural Science Foundation of Chongqing,No.CSTB2023NSCQ-mSX0561(to WL).
Effective treatment methods for stroke,a common cerebrovascular disease with a high mortality rate,are still being sought.Exosome therapy,a form of acellular therapy,has demonstrated promising efficacy in various dise...
关键词：angiogenesis animal model cerebrovascular disorder extracellular vesicle mortality rates neural stem cell NEUROINFLAMMATION oxidative stress programmed cell death therapy 
Exploring the significance of extracellular vesicles:Key players in advancing cancer and possible theranostic tools
《Cancer Pathogenesis and Therapy》2025年第2期109-119,共11页Bhaumik Patel Shreyas Gaikwad Sahdeo Prasad 
Metastasis remains a critical challenge in cancer treatment and the leading cause of cancer-related mortality.Ongoing research has demonstrated the key role of extracellular vesicles(EVs)in facilitating communication ...
关键词：Extracellular vesicle(EV) Cancer metastasis BIOMARKER Bioengineered EV 
Strategies for Small Extracellular Vesicle-Based Cancer Immunotherapy
《Research》2025年第1期765-781,共17页Yundi Chen Shasha Tang Fengfeng Cai Yuan Wan 
supported by the National Cancer Institute(grants R01CA230339 and R37CA255948).
Extracellular vesicles(EVs)are lipid bilayer-enclosed vesicles released by cells.EVs encapsulate proteins and nucleic acids of their parental cell and efficiently deliver the cargo to recipient cells.These vesicles ac...
关键词：extracellular vesicles therapeutic agents liquid biopsy extracellular vesicles evs drug delivery mediators intercellular communication drug delivery vehiclestherapeutic agentsand cancer immunotherapy 
An insect cell-derived extracellular vesicle-based gB vaccine elicits robust adaptive immune responses against Epstein-Barr virus
《Science China(Life Sciences)》2025年第3期734-745,共12页Qian Wu Kaiyun Chen Wenhui Xue Guosong Wang Yanbo Yang Shaowei Li Ningshao Xia Yixin Chen 
supported by the National Natural Science Foundation of China(82073756).
Epstein-Barr virus(EBV),the first identified human tumor virus,is implicated in various human malignancies,infectious mononucleosis,and more recently,multiple sclerosis.Prophylactic vaccines have the potential to effe...
关键词：Epstein-Barr virus glycoprotein gB extracellular vesicle humoral immune responses cellular immune responses 
Biphasic glucose-stimulated insulin secretion over decades:a journey from measurements and modeling to mechanistic insights
《Life Metabolism》2025年第1期5-15,共11页Xiaohong Peng Kai Wang Liangyi Chen 
the National Center for Protein Sciences at Peking University in Beijing,China;supported by the National Natural Science Foundation of China(81925022,T2288102,and 32227802);the National Key Research and Development Program of China(2022YFC3400600);the Beijing Natural Science Foundation(Z20J00059 and 7244366);the Fundamental Research Funds for the Central Universities(PKU2024XGK011);supported by the New Cornerstone Science Foundation;the High-performance Computing Platform of Peking University.
Glucose-stimulated insulin release from pancreaticβ-cells is critical for maintaining blood glucose homeostasis.An abrupt increase in blood glucose concentration evokes a rapid and transient rise in insulin secretion...
关键词：glucose-stimulated insulin secretion vesicle pools readily releasableβ-cells β-cell heterogeneity 
Seasonal influence on miRNA expression dynamics of extracellular vesicles in equine follicular fluid
《Journal of Animal Science and Biotechnology》2025年第1期136-152,共17页Jean M.Feugang Ahmed Gad Nico G.Menjivar Ghassan M.Ishak Samuel Gebremedhn Melba O.Gastal Notsile H.Dlamini Radek Prochazka Eduardo L.Gastal Dawit Tesfaye 
Southern Illinois University,Carbondale,IL;Ministry of Higher Education&Scientific Research,Baghdad,Iraq;NIFA-USDA Hatch project accession#1016077(Multistate#W4171);USDAARS project 6066-31000-015-00D;NIH MS-IDeA network of Biomedical Research Excellence award 5P20GMI03476-19.GMI received a PhD scholarship from the Ministry of Higher Education&Scientific Research,Baghdad,Iraq.
Background Ovarian follicular fluid(FF)is a dynamic environment that changes with the seasons,affecting follicle development,ovulation,and oocyte quality.Cells in the follicles release tiny particles called extracellu...
关键词：Extracellular vesicle Follicle growth Follicular fluid HORSE MARE OVULATION Pre-ovulation Seasonal breeding 
Differential expression of plasma extracellular vesicle miRNAs as biomarkers for distinguishing psoriatic arthritis from psoriasis
《Chinese Medical Journal》2025年第2期219-221,共3页Kexiang Yan Jie Zhu Mengmeng Zhang Fuxin Zhang Bing Wang Ling Han Qiong Huang Yulong Tang Yuan Li Nikhil Yawalkar Zhenghua Zhang Zhenmin Niu 
funded by the National Key Research and Development Program of China(No.2023YFC2508100);the National Natural Science Foundation of China(Nos.81773322,82173420,81673054,81673073,and 81974471);the Shanghai Municipal Commission of Health and Family Planning(No.2023ZZ02018);the Shanghai Municipal Key Clinical Specialty(No.shslczdzk01002);the Natural Science Foundation of Shanghai(No.20ZR1440100);the Key Project in Basic Research Advocated by Shanghai Science and Technology Commission(No.13JC1402300);the Clinical Research Plan of SHDC(Nos.SHDC2020CR6022,SHDC2020CR1014B,SHDC22022302,and SHDC2024CRI052).
To the Editor:Psoriatic arthritis(PsA)affects up to 30%of patients with psoriasis,contributing to a decreased quality of life.PsA can involve a variety of clinical manifestations,including peripheral and axial arthrit...
关键词：PSORIASIS identify biomarkers differential expression plasma extracellular vesicle psoriatic arthritis biomarkers 
Recent progress in the applications of presynaptic dopaminergic positron emission tomography imaging in parkinsonism
《Neural Regeneration Research》2025年第1期93-106,共14页Yujie Yang Xinyi Li Jiaying Lu Jingjie Ge Mingjia Chen Ruixin Yao Mei Tian Jian Wang Fengtao Liu Chuantao Zuo 
supported by the Research Project of the Shanghai Health Commission,No.2020YJZX0111(to CZ);the National Natural Science Foundation of China,Nos.82021002(to CZ),82272039(to CZ),82171252(to FL);a grant from the National Health Commission of People’s Republic of China(PRC),No.Pro20211231084249000238(to JW);Medical Innovation Research Project of Shanghai Science and Technology Commission,No.21Y11903300(to JG).
Nowadays,presynaptic dopaminergic positron emission tomography,which assesses deficiencies in dopamine synthesis,storage,and transport,is widely utilized for early diagnosis and differential diagnosis of parkinsonism....
关键词：aromatic amino acid decarboxylase brain imaging dopamine transporter Parkinson’s disease PARKINSONISM positron emission tomography presynaptic dopaminergic function vesicle monoamine transporter type 2 
Considerations regarding the application of Chinese herbal medicine-derived extracellular vesicle-like particles in a drug delivery system
《Acupuncture and Herbal Medicine》2024年第4期423-426,共4页Fucai Chen Yingjie Zhang Yu Zheng Longxiang Pan Jiale Li Liuqing Di Peng Cao Ruoning Wang 
supported by National Natural Science Foundation of China(82125037,82274104,82074024,82374042);Jiangsu Provincial Medical Innovation Center(CXZX202225);Natural Science Foundation Youth Project of Nanjing University of Chinese Medicine(NZY81903557);the Open Project of Chinese Materia Medica First-Class Discipline of Nanjing University of Chinese Medicine(2020YLXK019);Young Elite Scientists Sponsorship Program by CACM(2021-QNRC2-A01).
“Chinese herbal medicine extracellular vesicles-like particles”(CHM-EVLPs)refer to vesicle-like nanoparticles secreted by Chinese herbal medicines.These particles possess a lipid bilayer framework and contain variou...
关键词：HERBAL application utilizing 
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