高通量测序技术在食源性病原体快速检测中的应用进展  

The Application of High-throughput Sequencing Technology in the Rapid Detection of Foodborne Pathogens

作　　者：付博菲[1] 朱晓龙[2] 邱斌[3] FU Bo-fei;ZHU Xiao-long;QIU Bin(Tianjin Normal University,Tianjin 300387,China;Tianjin Medical University,Tianjin 300070,China;Institute of Agro-Food Science and Technology,Shandong Academy of Agricultural Science,Shandong,China Provincial Key Laboratory of Agro-Products Processing Technology,Key Laboratory of Novel Food Resources Processing,Ministry of Agriculture,Jinan 250100,Shandong,China)

机构地区：[1]天津师范大学,天津300387 [2]天津医科大学,天津300070 [3]山东省农业科学院农产品研究所山东省农产品精深加工技术重点实验室农业部新食品资源加工重点实验室,山东济南250100

出　　处：《食品研究与开发》2019年第3期200-205,共6页Food Research and Development

基　　金：天津师范大学教育管理基金资助(52WT1505);国家自然科学基金青年基金(31401487)

摘　　要：探讨高通量测序技术在食源性致病病原体早期检测方面的应用,以充分显示高通量测序技术在食品快速检测、预防食源性疾病传播、疫情调查及作为精细化食品安全管理手段等方面的巨大潜力。评价该技术的优势及缺陷,同时对其在食源性病原体快速检测的应用前景进行展望,以期推动、完善高通量技术在食品安全领域的应用。The applications of high-throughput sequencing technology(HTS)in the rapid detection of foodborne pathogens were discussed.The great potential of HTS in managing food safety,preventing of foodborne disease spreading,investigating outbreak,and refining food safety management was fully demonstrated.The limitations and advantages of the technique were appraised.The application prospect in rapid detection of foodborne pathogens was prospected.The future prospects of the rapid detection of foodborne pathogens were presented as well,with a view to promoting and improving the application of HTS in food safety.

关 键 词：食品微生物 食源性病原体 高通量测序技术 快速检测 

分 类 号：R155.5[医药卫生—营养与食品卫生学]