α地中海贫血筛查及诊断技术的进展  

Progress in screening and diagnostic techniques for α-thalassemia

作　　者：沈茹[1] 陈云明 杨晓红[1] 王晓岩 SHEN Ru;CHEN Yunming;YANG Xiaohong;WANG Xiaoyan(Lobaratory Department of Kunming Children's Hospital,Kunming,Yunnan,China,650028;Lobaratory Department of Shilin Yi nationality Autonomous County people's Hospital,Kunming,Yunnan,China, 652200;The 920 Hospital Cadre Ward of the Joint Service Support Unit of the Chinese people's Liberation Army,Kunming,Yunnan,China,650032)

机构地区：[1]昆明市儿童医院检验科,云南昆明650028 [2]昆明市石林彝族自治县人民医院检验科,云南昆明652200 [3]中国人民解放军联勤保障部队第九二○医院干部病房,云南昆明650032

出　　处：《分子诊断与治疗杂志》2019年第1期68-72,共5页Journal of Molecular Diagnostics and Therapy

基　　金：云南省重点研发计划项目国际科技合作专项(2018IA047)

摘　　要：α地中海贫血在我国东南沿海地区发病率高,预防和准确诊断该病尤为重要。先进的实验筛查及诊断技术,是预防及治疗α地中海贫血的基石。本文综述近年来α地中海贫血的相关实验诊断技术的进展,以期增加对不同的实验诊断技术及发展的了解,为各种技术方法的应用和改进拓宽视野和思路。Alpha thalassemia has a high incidence in the southeastern coastal areas of China,and it is important to prevent and diagnose the disease. Advanced experimental screening and diagnostic techniques are the cornerstones for the prevention and treatment of alpha thalassemia. In this article, the progress of related experimental diagnostic techniques for alpha thalassemia in recent years will be reviews,with a view to increasing understanding of different experimental diagnostic techniques and developments,and broadening horizons and ideas for the application and improvement of various technical methods.

关 键 词：Α地中海贫血 分子机制 筛查方法 基因诊断 

分 类 号：R556.61[医药卫生—血液循环系统疾病]