Comparative outcomes of subcutaneous and transvenous cardioverter-defibrillators  

作　　者：Jin-Jun Liang Hideo Okamura Roshini Asirvatham Andrew Schneider David O. Hodge Mei Yang Xu-Ping Li Ming-Yan Dai Ying Tian Pei Zhang Bryan C. Cannon Cong-Xin Huang Paul A. Friedman Yong-Mei Cha 

机构地区：[1]Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, China [2]Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905, USA [3]Division of Pediatric Cardiology, Mayo Clinic, Rochester, MN 55905, USA [4]Biostatistics Unit, Mayo Clinic, Jacksonville, FL 32224, USA

出　　处：《Chinese Medical Journal》2019年第6期631-637,共7页中华医学杂志（英文版）

摘　　要：Background: The comparative outcomes of subcutaneous implantable cardioverter-defibrillator (S-ICD) and transvenous (T-ICD) have not been well studied. The aim of this study was to evaluate the safety and efficacy of currently available S-ICD and T-ICD. Methods: The study included 86 patients who received an S-ICD and 1:1 matched to those who received single-chamber T-ICD by gender, age, diagnosis, left ventricular ejection fraction (LVEF), and implant year. The clinical outcomes and implant complications were compared between the two groups. Results: The mean age of the 172 patients was 45 years, and 129 (75%) were male. The most common cardiac condition was hypertrophic cardiomyopathy (HCM, 37.8%). The mean LVEF was 50%. At a mean follow-up of 23 months, the appropriate and inappropriate ICD therapy rate were 1.2% vs. 4.7%(X^2= 1.854, P=0.368) and 9.3% vs. 3.5%(X^2 = 2.428, P = 0.211) in S-ICD and T-ICD groups respectively. There were no significant differences in device-related major and minor complications between the two groups (7.0% vs. 3.5%, X^2 = 1.055, P = 0.496). The S-ICD group had higher T-wave oversensing than T-ICD group (9.3% vs. 0%, X^2 = 8.390, P=0.007). Sixty-five patients had HCM (32 in S-ICD and 33 in T-ICD). The incidence of major complications was not significantly different between the two groups. Conclusions: The efficacy of an S-ICD is comparable to that of T-ICD, especially in a dominantly HCM patient population. The S-ICD is assodated with fewer major complications demanding reoperation.

关 键 词：HYPERTROPHIC CARDIOMYOPATHY IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR Outcome SUBCUTANEOUS IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR 

分 类 号：R[医药卫生]