Soluble neuregulin-1(NRG1): a factor promoting peripheral nerve regeneration by affecting Schwann cell activity immediately after injury  

作　　者：Marwa El Soury Giovanna Gambarotta 

机构地区：[1]Department of Clinical and Biological Sciences, University of Torino

出　　处：《Neural Regeneration Research》2019年第8期1374-1375,共2页中国神经再生研究（英文版）

摘　　要：Neuregulin-1 (NRG1) is a well known growth factor playing contradictory roles in myelination depending on the existing isoform. Transmembrane NRG1 acts as a promyelinating factor, while the soluble isoform inhibits myelination. In this perspective, we would like to emphasize this conflicting role played by NRG1 isofbrms regarding their roles in myelination, remyelination and the entire process of peripheral nerve regeneration.

关 键 词：SOLUBLE NEUREGULIN-1 promoting PERIPHERAL INJURY 

分 类 号：R[医药卫生]