云南高校图书馆联盟文献共享服务平台- NEUREGULIN-1

NEUREGULIN-1: 作品数：53被引量：124H指数：6; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：冯灵美宋耀明刘超赵炜疆蔡季平更多>>; 相关机构：复旦大学广西医科大学第二军医大学复旦大学上海医学院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划湖北省自然科学基金广西研究生教育创新计划更多>>

Emerging role of neuregulin-1beta1 in pathogenesis and progression of multiple sclerosis: 《Neural Regeneration Research》2023年第1期133-134,共2页Seyyed Mohyeddin Ziaee Soheila Karimi-Abdolrezaee; supported by a University of Manitoba Graduate Fellowship;Graduate Enhancement of Tricouncil Supplement (GETS);Hillary Kaufman Lerner Memorial Funds;supported by the grants from Multiple Sclerosis Society of Canada (EGDI-2936, EGDI-3742);the Canadian Institute of Health Research (133721 and 156218); Multiple sclerosis(MS)is a chronic immune-mediated disorder of the central nervous system(CNS)that causes focal demyelinating lesions,followed by axonal and neuronal degeneration.Several genetic and environmental fact...; 关键词：PATHOGENESIS SCLEROSIS DEGENERATION

Neuregulin-1/ErbB4 upregulates acetylcholine receptors via Akt/mTOR/p70S6K:a study in a rat model of obstetric brachial plexus palsy and in vitro被引量：1: 《Acta Biochimica et Biophysica Sinica》2022年第11期1648-1657,共10页Jing Qiao Jiayu Sun Liang Chen Bo Li Yudong Gu; This work was supported by the grant from the National Natural Science Foundation of China(No.81672240 to L.C.).; In obstetric brachial plexus palsy(OBPP),the operative time window for nerve reconstruction of the intrinsic muscles of the hand(IMH)is much shorter than that of biceps.The reason is that the atrophy of IMH becomes ir...; 关键词：acetylcholine receptor subunits DENERVATION motor endplates obstetric brachial plexus palsy

Neuregulin-1对过氧化氢诱导的小鼠骨髓间充质干细胞衰老的影响: 《广西医科大学学报》2021年第5期864-870,共7页颜池张天蓉黄伟强; 国家自然科学基金资助项目(No.81760415;No.81960056);广西研究生教育创新计划资助项目(No.YCSW2020114);广西医疗卫生适宜技术研究与开发项目(No.S201518)。; 目的:探讨Neuregulin-1(NRG-1)对过氧化氢(H2O2)诱导的小鼠骨髓间充质干细胞(BMSCs)衰老的影响。方法:用H2O2诱导小鼠BMSCs衰老模型,将BMSCs分为对照组、H2O2组、H2O2+NRG-1组。采用CCK8检测细胞存活率,β-半乳糖苷酶染色法检测细胞衰老...; 关键词：骨髓间充质干细胞 NEUREGULIN-1 细胞衰老

Neuregulin-1/ErbB信号通路在组织工程中作用的研究进展被引量：3: 《口腔医学》2021年第2期177-182,共6页李玲葛少华; 国家自然科学基金(81670993,81873716)。; 组织工程的理想目标是利用生长因子、干细胞、支架系统维持、改善和修复受损的组织和器官。神经调节蛋白-1 (neuregulin-1, NRG-1)是一种内源性的生长因子,酪氨酸激酶受体(receptor tyrosine kinases, ErbB)是其发挥作用的重要受体。在...; 关键词：神经调节蛋白-1 酪氨酸激酶受体信号通路组织工程

Soluble neuregulin-1(NRG1): a factor promoting peripheral nerve regeneration by affecting Schwann cell activity immediately after injury被引量：4: 《Neural Regeneration Research》2019年第8期1374-1375,共2页Marwa El Soury Giovanna Gambarotta; Neuregulin-1 (NRG1) is a well known growth factor playing contradictory roles in myelination depending on the existing isoform. Transmembrane NRG1 acts as a promyelinating factor, while the soluble isoform inhibits my...; 关键词：SOLUBLE NEUREGULIN-1 promoting PERIPHERAL INJURY

Cornel iridoid glycoside protects against white matter lesions induced by cerebral ischemia via activation of neuregulin-1 pathway in rats: 《中国药理学与毒理学杂志》2019年第6期451-451,共1页WANG Ming-yang HUA Xue-si NIU Hong-mei SUN Zheng-yu ZHANG Li LI Ya-li ZHANG Lan LI Lin; Ischemic stroke often elicits profound white matter lesions, which results in poor neurological outcomes and impairing the recovery in post-stroke. However, few studies have focused on white matter lesions caused by c...; 关键词：cornel IRIDOID GLYCOSIDE white matter lesions cerebral ischemia BRAIN-DERIVED NEUROTROPHIC factor NEUREGULIN-1 PATHWAY

人参皂苷Rb3通过Neuregulin-1/ErbB信号通路对心肌梗死大鼠VE-cadherin,NRG-1,ErbB2,ErbB4表达的影响被引量：7: 《中国循证心血管医学杂志》2019年第2期195-199,共5页韩凌张晶晶秦立; 河南省科学技术成果(9412015J0308); 目的观察人参皂苷Rb3通过Neuregulin-1/ErbB信号通路对心肌梗死大鼠VE-cadherin,NRG-1,Erb B2,Erb B4表达的影响。方法 60只大鼠随机分为Sham组、Model组、G-Rb3-L组(10 mg/kg)、G-Rb3-M组(20 mg/kg)、G-Rb3-H组(40 mg/kg)及阳性药物组...; 关键词：人参皂苷RB3 心肌梗死 NRG-1/ErbB信号通路 VE-CADHERIN

Neuregulin-1及其受体ErbB在中枢神经系统损伤修复中作用的研究进展被引量：2: 《神经解剖学杂志》2019年第1期83-87,共5页王艳雪李坪张歆悦吴海鹰; 国家自然科学基金资助项目(31100769);云南省医疗卫生内设研究机构项目(2017NS065);云南省哲学社会规划项目(YB2016031); 神经调节蛋白-1(NRG-1)是一类包含表皮生长因子样结构域,在神经组织中发挥着多种生物学效应的营养因子。在神经损伤时,NRG-1的作用涉及神经元迁移、轴突生长、髓鞘和突触的形成,以及促进神经再生,近年来受到越来越多的关注,文中将对NRG-...; 关键词：神经调节蛋白-1 ErbB受体中枢神经系统损伤

Changes in nitric oxide,angiotensinⅡ,angiopoietin-like protein 4 mRNA,neuregulin 1 mRNA,and platelet endothelial cell adhesion molecule-1 in rats with acute blood stasis induced by high-molecular-weight dextran被引量：3: 《Journal of Traditional Chinese Medicine》2017年第6期846-853,共8页Feng Yu Zhang Junxiu Li Shaodan Liu Yi Zhang Yin Guo Yunxia Yang Minghui; Supported by the National Program on Key Basic Research Project(973 Program:Study of Choroid Theory Based On Cardiac Cerebrovascular Disease.No.2012CB518601); OBJECTIVE: To investigate the influence of acute blood stasis on nitric oxide(NO), angiotensin Ⅱ(Ang Ⅱ), angiopoietin-like protein 4(ANGPTL4)m RNA, neuregulin 1(NRG-1) m RNA, and platelet endothelial cell adhesion m...; 关键词：Blood stasis Basic theory of TraditionalChinese Medicine Endothelial cells ANGIOTENSIN Ⅱ NEUREGULIN-1 Antigens CD31

Neuregulin-1/ErbBs信号通路在慢性心力衰竭中的研究进展被引量：5: 《中国药理学通报》2017年第11期1481-1484,共4页赵齐飞魏聪李红蓉任红; 国家重点基础研究发展计划(973计划)资助项目(No2012CB518606); 神经调节蛋白-1(neuregulin-1,NRG-1)与酪氨酸激酶Erb Bs受体在心血管系统中广泛表达,具有稳定心肌细胞结构和功能、促进细胞增殖和存活、抑制细胞凋亡、抑制心肌纤维化、改善心肌能量代谢、促进血管新生等多种功能,在慢性心力衰竭(chro...; 关键词：神经调节蛋白-1 酪氨酸激酶受体心肌细胞凋亡心肌纤维化心室重构慢性心力衰竭

NEUREGULIN-1