Left colonic metastasis from primary hepatocellular carcinoma: A case report  

作　　者：Fulvio Tagliabue Morena Burati Marco Chiarelli Alessandro Marando Matilde De Simone Ugo Cioffi 

机构地区：[1]Department of Emergency and Robotic Surgery,Ospedale“A Manzoni”Lecco via Dell’Eremo 9/11,Lecco 23900,Italy [2]Department of Pathology,Ospedale“A Manzoni”Lecco via Dell’Eremo 9/11,Lecco 23900,Italy [3]Department of Surgery,University of Milan,Milano 20122,Italy

出　　处：《World Journal of Clinical Cases》2019年第15期2044-2048,共5页世界临床病例杂志

摘　　要：BACKGROUND Hepatocellular carcinoma(HCC)accounts for 5-6%of all human cancers.Considering the extrahepatic metastasis,the main organs involved are lymphnodes,lung,bone and adrenal gland.Usually colon metastasis is very rare,especially on the left sided colon.CASE SUMMARY We report a case of a 70 years-old man hepatitis B carrier with HCC treated four times with trans-arterial chemoembolization,presented to our surgical department complaining of gastrointestinal bleeding.A colonoscopy revealed a mass of 4 cm of the sigmoid colon with signs of bleeding.The computed tomography showed a mass originated from the sigmoid colon of 3.5 cm,and the presence of HCC in segment VI and VII,without portal vein thrombosis.Due to the large size of the mass and the active bleeding,the patient underwent a left colectomy.The postoperative period was uneventful,and the patient was discharged in fifth post-operative day.Histological examination revealed that the neoplasm was characterized by a diffuse proliferation of epithelial cells with an hepatoid differentiation.So,the presence of a history of HCC of the liver and the histopathological features supported the diagnosis of metastasis from the liver.CONCLUSION Although rare,colon metastasis from an HCC can be left-sided and can present with acute bleeding.BACKGROUND Hepatocellular carcinoma(HCC) accounts for 5-6% of all human cancers.Considering the extrahepatic metastasis, the main organs involved are lymphnodes, lung, bone and adrenal gland. Usually colon metastasis is very rare,especially on the left sided colon.CASE SUMMARY We report a case of a 70 years-old man hepatitis B carrier with HCC treated four times with trans-arterial chemoembolization, presented to our surgical department complaining of gastrointestinal bleeding. A colonoscopy revealed a mass of 4 cm of the sigmoid colon with signs of bleeding. The computed tomography showed a mass originated from the sigmoid colon of 3.5 cm, and the presence of HCC in segment VI and VII, without portal vein thrombosis. Due to the large size of the mass and the active bleeding, the patient underwent a left colectomy. The postoperative period was uneventful, and the patient was discharged in fifth post-operative day. Histological examination revealed that the neoplasm was characterized by a diffuse proliferation of epithelial cells with an hepatoid differentiation. So, the presence of a history of HCC of the liver and the histopathological features supported the diagnosis of metastasis from the liver.CONCLUSION Although rare, colon metastasis from an HCC can be left-sided and can present with acute bleeding.

关 键 词：HEPATOCELLULAR CARCINOMA COLON METASTASIS Case REPORT 

分 类 号：R[医药卫生]