Takotsubo syndrome: The past, the present and the future  

作　　者：Nauman Khalid Pooja Sareen Sarah Aftab Ahmad Lovely Chhabra 

机构地区：[1]Section of Interventional Cardiology,MedStar Washington Hospital Center,Washington,DC 20010,United States [2]Department of Medicine,Harrisburg Medical Center,Harrisburg,IL 62946,United States [3]Department of Cardiovascular Surgery,Saint Francis Medical Center,Monroe,LA 71201,United States [4]Department of Cardiology,Heartland Regional Medical Center,Marion,IL 62959,United States

出　　处：《World Journal of Cardiology》2019年第9期213-216,共4页世界心脏病学杂志（英文版）（电子版）

摘　　要：Takotsubo syndrome is a wide spectrum disease with a dramatic clinical presentation mimicking acute coronary syndrome albeit without obstructive coronary disease and typically manifests in the backdrop of intense emotional or physical trigger.Pathophysiology is incompletely understood with multifactorial mechanistic pathways circling around a heart-brain-endocrine axis.Several anatomic and phenotypic variants exist with varied clinical manifestations.The aftermath of Takotsubo syndrome is not always benign and both short-and longterm complications can occur which may impact its prognosis.Several gaps in knowledge exist providing an impetus for tremendous future research opportunities.Takotsubo syndrome is a wide spectrum disease with a dramatic clinical presentation mimicking acute coronary syndrome albeit without obstructive coronary disease and typically manifests in the backdrop of intense emotional or physical trigger. Pathophysiology is incompletely understood with multifactorial mechanistic pathways circling around a heart-brain-endocrine axis. Several anatomic and phenotypic variants exist with varied clinical manifestations. The aftermath of Takotsubo syndrome is not always benign and both short-and longterm complications can occur which may impact its prognosis. Several gaps in knowledge exist providing an impetus for tremendous future research opportunities.

关 键 词：TAKOTSUBO syndrome TRIGGERS PATHOPHYSIOLOGY ANATOMIC VARIANTS Prognosis 

分 类 号：R[医药卫生]