2015-2018年福建省食源性疾病沙门氏菌监测情况分析  

Surveillance situation of Salmonella in foodborne diseases in Fujian,China,2015-2018

作　　者：刘雪杰[1,2] 陈伟伟 傅祎欣[1] 叶玲清 李闽真 马群飞[1] LIU Xue-jie;CHEN Wei-wei;FU Yi-xin;YE Ling-qing;LI Min-zhen;MA Qun-fei(Fujian Center for Disease Control and Prevention,Fuzhou 350001,China;Key Laboratory of Fujian Province for Zoonotic Disease Research,Fuzhou 350001,China)

机构地区：[1]福建省疾病预防控制中心,福州350001 [2]福建省人兽共患病研究重点实验室,福州350001

出　　处：《中国人兽共患病学报》2020年第3期223-228,共6页Chinese Journal of Zoonoses

基　　金：福建省科技计划项目(No.2018Y0008)资助。

摘　　要：目的研究2015-2018年福建省哨点医院食源性疾病沙门氏菌感染情况、血清型分布、耐药特征、病因性食品来源,以了解福建省重要食源性疾病的发生情况。方法对10家哨点医院分离的707株沙门氏菌进行血清学分型,依据CLSI推荐的药敏试验抗生素选择原则、选取14种抗生素进行药敏试验,并对病因性食品进行统计分析。结果707株沙门氏菌主要是鼠伤寒沙门氏菌(57.85%)、其次是肠炎沙门氏菌(15.42%),共涵盖43个血清型;病因性食品以粮食及其制品为主(22.21%),其次是乳与乳制品(16.31%);在对14种抗生素的药敏试验中,沙门氏菌对氨苄西林耐药率最高(73.39%),其次是四环素(68.53%)、头孢唑林(54.65%)。对亚胺培南耐药率最低(1.72%),多重耐药菌逐年增多。结论继续加强食源性疾病监测,提高食品安全隐患的早期识别、预警与防控能力。同时加强食品监管力度,从源头预防控制食源性感染。临床应结合药敏结果,制定合理用药方案,以降低抗生素耐药性影响。This study aimed to investigate the infection situation,main serotypes distribution,antibiotic resistance,and source of etiological food of Salmonella in foodborne diseases patients in Fujian Province from 2015 to 2018.A total of 707 Salmonella strains were isolated from diarrhea patients in 10 sentinel hospitals in Fujian Province from 2015 to 2018.And the total of 707 Salmonella strains were studied on serological classification,traceability of etiological food and antibiotic resistance.According to the principle of selecting antibiotics for drug sensitivity test recommended by CLSI,14 kinds of antibiotics were selected for drug sensitivity test in our study.These results shown that the dominant serotype was S.typhimurium(57.85%),followed by S.enteritidis(15.42%),covering 43 serotypes.The etiological food mainly was Grains and their Product(22.21%),followed by milk and milk-products(16.31%).The 14 kinds of antibiotics were chose in our study.The resistance rate to ampicillin was the highest(73.39%),followed by tetracycline(68.53%),cefazolin(54.65%).Multidrug resistance bacteria increased year by year.Food-borne disease surveillance should be strengthened to improve the ability of early identification,early warning and prevention and control of food safety risks.Meanwhile,food supervision should be strengthened to prevent and control food-borne infections from the source.We should formulate a rational drug regimen based on drug sensitivity results to reduce the negative effect from of antibiotic resistance.

关 键 词：食源性疾病 沙门氏菌 血清分型 病因性食品 耐药 

分 类 号：R378.2[医药卫生—病原生物学]