毛木耳多糖分离纯化方法及生物活性研究进展  

Research progress on biological activities and separation and purification methods of polysaccharides from Auricularia polytricha(Mont.) Sacc.

作　　者：苗晶囡 徐丹 李海霞[1] 余邦良[1] 周丹[1] 吴良[1] 邱军强 张华[4] 韩伟 MIAO Jing-Nan;XU Dan;LI Hai-Xia;YU Bang-Liang;ZHOU Dan;WU Liang;QIU Jun-Qiang;ZHANG Hua;HAN Wei(School of Pharmacy,Hainan Medical University,Haikou 570100,China;Hainan Key Laboratory for Research and Development of Tropical Herbs,Haikou 570100,China;Key Laboratory of Tropical Translational Medicine of Ministry of Education,Haikou 570100,China;Harbin Institute of Technology,Harbin 150010,China;Guizhou University of Traditional Chinese Medicine,Guiyang 550002,China)

机构地区：[1]海南医学院药学院,海口570100 [2]海南省热带药用植物研究开发重点实验室,海口570100 [3]教育部热带转化医学重点实验室,海口570100 [4]哈尔滨工业大学化工学院,哈尔滨150010 [5]贵州中医药大学药学院,贵阳550002

出　　处：《食品安全质量检测学报》2020年第10期3059-3066,共8页Journal of Food Safety and Quality

基　　金：黑龙江省自然科学基金项目(C2018034);中央高校基础研究基金项目(HIT.NSRIF.2020024);黑龙江省博士后研究启动基金项目(LBH-Q19104)。

摘　　要：食用菌作为一种独特的天然资源,其在保健食品和医药领域的应用受到广泛关注。毛木耳为我国常见的药食同源大型食用菌。毛木耳的多种生物活性与其含有丰富的多糖密切相关。毛木耳多糖(Auricularia polytricha (Mont.) Sacc.polysaccharides,APP)的提取、分离纯化及生物活性等对其深度开发具有重要意义。本文通过查阅国内外近年来有关APP的提取、分离纯化、化学结构研究、生物活性及其作用机制的研究文献并进行总结归纳,分析了毛木耳多糖的研究现状,总结了存在的问题,在此基础上对毛木耳多糖的研究进行了展望,旨在为毛木耳多糖的进一步开发利用提供参考。As a unique natural resource,edible mushroom has drawn wide attention for its advantages of application in health food and medicine.Auricularia polytricha(Mont.) Sacc.is a common large-type medical and edible fungus.Various of biological activities of Auricularia polytricha(Mont.) Sacc.closely related to the polysaccharides in it.The extraction,isolation and purification,and biological activity of Auricularia polytricha(Mont.) Sacc.polysaccharide(APP) are of great significance to the depth of the development of APP.This paper summarized the progress on the extraction,separation and purification,chemical structure research,biological activities and mechanism of the action of APP by referring to the relevant literatures on the extraction,purification and biological activity of APP from at home and abroad in recent years,analyzed the research status of Auricularia polytricha(Mont.) Sacc.polysaccharides,and summarized the existing problems,thus to provide references for the further development and utilization of APP.

关 键 词：毛木耳 多糖 分离纯化 生物活性 

分 类 号：TS201.23[轻工技术与工程—食品科学]