胃肠道间质瘤诊断技术进展  

Advances in diagnosis of gastrointestinal stromal tumor

作　　者：陈凯丽 张楠[2] 张擎 成洪聚 Chen Kaili;Zhang Nan;Zhang Qing;Cheng Hongju(Department of Clinical Medicine,School of Clinical Medicine,Jining Medical University,Jining,Shandong 272067,China;Department of Clinical Medicine,School of the Second Clinical Medicine,Jining Medical University,Jining,Shandong 272067,China;Department of Psychiatry,School of Mental Health,Jining Medical University,Jining,Shandong 272067,China;Department of Physiology,College of Basic Medicine,Jining Medical University,Jining,Shandong 272067,China)

机构地区：[1]济宁医学院临床医学院临床医学系,272067 [2]济宁医学院第二临床医学院临床医学系,272067 [3]济宁医学院精神卫生学院精神医学系,272067 [4]济宁医学院基础医学院生理学教研室,272067

出　　处：《中国基层医药》2020年第16期2045-2048,共4页Chinese Journal of Primary Medicine and Pharmacy

基　　金：山东省高等学校科技计划资助项目(J18KB119);国家级大学生创新创业训练计划项目(201810443032)。

摘　　要：胃肠道间质瘤(GIST)是消化系统最常见间叶源性肿瘤,具有潜在恶性倾向。随着生活习惯的变化和仪器设备的更新,GIST发病率和检出率逐年升高,因而备受关注,但其临床表现无特征性。目前主要通过CT、MRI等影像学技术初诊,病理学检测为其诊断的金指标。近年来随着免疫组化技术和基因技术的发展,免疫标志物和基因检测对GIST的诊断日趋重要。笔者对GIST诊断技术进展进行综述。Gastrointestinal stromal tumor(GIST)is the most common mesenchymal tumor in the digestive system,with potential malignant tendency.With the change of living habits and the update of instruments and equipments,the morbidity and detection rate of GIST have been increased year by year,attracting much attention.However,its clinical manifestations are not characteristic.At present,primary diagnosis is mainly made by imaging techniques such as CT and MRI,and pathological diagnosis is the gold index.In recent years,with the development of immunohistochemical technology and gene technology,immune markers and gene detection play an increasingly important role in the diagnosis of GIST.This paper reviews the progress of GIST diagnostic techniques.

关 键 词：胃肠肿瘤 胃肠道间质瘤 体层摄影术 发射型计算机 单光子 磁共振成像 超声检查 内窥镜检查 病理学 临床 免疫测定 基因测定 

分 类 号：R735[医药卫生—肿瘤]