益生菌ABC转运体寡糖结合蛋白的结构学研究进展  

Research Progress in the Structure of Oligosaccharide Binding Proteins of ABC Transporter in Probiotics

作　　者：苏思韵 杨思婷 张宇博 周志立 黄珍金 钟先锋 黄桂东 SU Si-yun;YANG Si-ting;ZHANG Yu-bo;ZHOU Zhi-li;HUANG Zhen-jin;ZHONG Xian-feng;HUANG Gui-dong(Guangdong Engineering Research Center for Traditional Fermentational Food,Guangdong Engineering Research Center for Safety Control of Food Circulation,Foshan Engineering Research Center for Brewing Technology,Foshan Engineering Research Center for Agricultural Biological Manufacturing,Department of Food Science,Foshan University,Foshan 528231,China)

机构地区：[1]佛山科学技术学院食品科学与工程学院,广东省传统发酵食品工程技术研究中心,广东省食品流通安全控制工程技术研究中心,佛山市酿造工程技术研究中心,佛山农业生物制造工程技术研究中心,广东佛山528231

出　　处：《食品工业科技》2020年第17期327-334,共8页Science and Technology of Food Industry

基　　金：国家自然科学基金项目(31660459,31700056);广东省自然科学基金项目(2018A0303130275,2020A1515011444);佛山科学技术学院研究生自由探索基金项目(2019ZYTS12)。

摘　　要：益生菌有助于改善宿主的微生态平衡。益生菌摄入寡糖有益于其增殖和代谢,该摄入过程主要是通过ABC转运体完成。ABC转运体的底物结合蛋白能够在胞外区域结合寡糖,并通过跨膜区进一步将其传递。本论文对近年来在益生菌中解析的寡糖结合蛋白进行综述,着重介绍其结构特性,并对其寡糖底物的功能机制进行探讨。Probiotics help improve the host’s microecological balance.Intake of oligosaccharides by probiotics is beneficial to its proliferation and metabolism.The intake process is mainly completed by ABC transporters.The substrate-binding protein of the ABC transporter is capable of binding oligosaccharides in the extracellular region and transmitting them further through the transmembrane region.This paper reviews the oligosaccharide-binding proteins in probiotics in recent years,highlights their structural characteristics,and discusses the functional mechanisms of their oligosaccharide substrates.

关 键 词：益生菌 寡糖结合蛋白 ABC转运体 共性 结构特性 

分 类 号：TS207.3[轻工技术与工程—食品科学]