Anticholinergic medications even in therapeutic range can cause recurrence of psychosis  

作　　者：Soumitra Das Seshadri Sekhar Chatterjee Barikar Chandrappa Malathesh 

机构地区：[1]Psychiatry,Northwestern Mental Health,Melbourne,Victoria,Australia [2]Psychiatry,Diamond Harbour Medical College,Diamond Harbour,India [3]Psychiatry,National Institute of Mental Health and Neuro Sciences,Bangalore,India

出　　处：《General Psychiatry》2020年第4期245-246,共2页综合精神医学（英文）

摘　　要：Anticholinergic drugs are commonly used in psychiatry to attenuate antipsychotic induced extrapyramidal syndrome(EPS).Psychosis as a side effect is generally explained under the rubric of anticholinergic toxicity or induced delirium.Anticholinergic induced worsening of psychosis in patients with normal cognition is extremely rare in literature.Here,we arepresenting a case of young female who was prescribed with multiple anticholinergics to reduce EPS,and each time had worsening of psychosis with intact cognition.We then discussed the possible neurobiological explanation with special reference to muscarinic hypothesis of schizophrenia.

关 键 词：CHOLINERGIC drugs PRESCRIBED 

分 类 号：R749.3[医药卫生—神经病学与精神病学]