一种检测铜离子的荧光探针及其应用  

A fluorescent probe for the detection of Cu and its application

作　　者：武小明 王皓[1] 杨绍祥[1] 田红玉[1] 刘永国[1] WU Xiaoming;WANG Hao;YANG Shaoxiang;TIAN Hongyu;LIU Yongguo(Beijing Advanced Innovation Center for Food Nutrition and Human Health,Beijing Key Laboratory of Flavor Chemistry,School of Light Industry,Beijing Technology and Business University,Beijing 100048,China)

机构地区：[1]北京食品营养与人类健康高精尖创新中心,北京市食品风味化学重点实验室,北京工商大学轻工科学技术学院,北京100048

出　　处：《精细化工》2020年第9期1769-1774,共6页Fine Chemicals

基　　金：国家自然科学基金项目(31901770);“十三五”时期北京市属高校高水平教师队伍建设支持计划青年拔尖人才培育计划(CIT&TCD201804021)。

摘　　要：以2-吡啶甲酰氯和E-2-苯并噻唑-3-(6-羟基萘)丙烯腈为原料,经过酯化反应,得到1个Cu2+荧光探针(E)-6-[2-(苯并噻唑-2-基)-2-氰基乙烯基]-2-萘吡啶甲酸酯(P1)。通过1HNMR、13CNMR、高分辨质谱对其结构进行表征,同时对其荧光性能进行测试。结果表明,该荧光探针能够高灵敏性、高选择性地识别Cu2+,对Cu2+的检测浓度范围是0~200μmol/L,检测限是17 nmol/L。该探针被成功用于检测葡萄酒和啤酒中Cu2+的质量浓度,其添加回收率为90.00%~108.30%。为开发识别性能良好,实用性强的Cu2+检测方法提供了参考。(E)-6-[2-(benzo[d] thiazol-2-yl)-2-cyanoviny] naphthalen-2-yl picolinate, a fluorescent probe(P1) for the detection of Cu2+ was synthesized by esterification between pyridine-2-carbonyl chloride and 2-benzothiazol-2-yl-3-(6-hydroxy-naphthalen-2-yl)acrylonitrile and characterized by 1 HNMR, 13 CNMR and HRMS. The fluorescence property was tested. The results showed that the fluorescent probe could recognize Cu2+ with high sensitivity and high selectivity. The detection range of Cu2+ was 0~200 μmol/L, and the detection limit was 17 nmol/L. The probe was used to detect Cu2+ in wine and beer, and the recovery rate of Cu2+ was 90.00%~108.30%. This study provides a reference for the development of Cu2+ detection method with good recognition performance and strong practicability.

关 键 词：铜离子 葡萄酒 荧光探针 快速检测 功能材料 

分 类 号：TS207.3[轻工技术与工程—食品科学]