一例鼠药中毒事件的应急检测  

Emergency detection of a case of rodenticide poisoning

作　　者：陈慧玲[1] 康莉[1] 廖仕成[1] 许欣欣[1] 姜杰[1] 毛丽莎[1] 刘红河[1] CHEN Hui-Ling;KANG Li;LIAO Shi-Cheng;XU Xin-Xin;JIANG Jie;MAO Li-Sha;LIU Hong-He(Shenzhen Center for Disease Control&Prevention,Shenzhen 518055,China)

机构地区：[1]深圳市疾病预防控制中心,深圳518055

出　　处：《食品安全质量检测学报》2020年第19期6926-6935,共10页Journal of Food Safety and Quality

基　　金：深圳市三名工程项目(SZSM201811070)。

摘　　要：目的对深圳市一起鼠药中毒事件进行应急检测。方法样品经过处理后,采用高效液相色谱-串联质谱法进行测定,确定中毒情况后,采用气相色谱-质谱联用法进行复查,外标法定量。结果血样及药物样品中均检测出毒鼠强,浓度分别为55μg/L、39.2 mg/kg。结论本次食物中毒事件是由于食用了含有毒鼠强的药物所致,市民应加强食品安全意识。Objective To test a rodenticide poisoning in Shenzhen. Methods After treatment, the samples were determined by high performance liquid chromatography-tandem mass spectrometry(HPLC-MS/MS), reexaminated by gas chromatography-mass spectrometry(GC-MS) and quantified by external standard method after determining the poisoning situation. Results Tetramine was detected in blood samples and drug samples, and the concentrations were 55 μg/L and 39.2 mg/kg respectively. Conclusion This food poisoning incident was caused by taking the drugs containing tetramine. The public should strengthen the awareness of food safety.

关 键 词：食物中毒 鼠药 毒鼠强 应急检测 

分 类 号：R155.3[医药卫生—营养与食品卫生学]