Recurrent deletions in the SARS-CoV-2 spike glycoprotein drive antibody escape  

作　　者：Kevin R McCarthy 

机构地区：[1]不详

出　　处：《四川生理科学杂志》2021年第1期86-86,共1页Sichuan Journal of Physiological Sciences

摘　　要：Zoonotic pandemics,like that caused by SARS-CoV-2,can follow the spillover of animal viruses into highly susceptible human populations.Their descendants have adapted to the human host and evolved to evade immune pressure.Coronaviruses acquire substitutions more slowly than other RNA viruses,due to a proofreading polymerase.In the spike glycoprotein,we find recurrent deletions overcome this slow substitution rate.

关 键 词：GLYCOPROTEIN OVERCOME slowly 

分 类 号：R73[医药卫生—肿瘤]