廉价废弃物厌氧发酵制备生物己酸技术进展  

Advances of biocaproate production from cost-effective substrates via anaerobic fermentation

作　　者：张存胜 杨莉 刘岩 霍书豪[1] ZHANG Cun-sheng;YANG Li;LIU Yan;HUO Shu-hao(School of Food and Biological Engineering,Jiangsu University,Zhenjiang 212013,China)

机构地区：[1]江苏大学食品与生物工程学院,江苏镇江212013

出　　处：《高校化学工程学报》2021年第2期215-222,共8页Journal of Chemical Engineering of Chinese Universities

基　　金：国家自然科学基金(51608232,21978120);江苏大学大学生科研立项项目(Y19A099)。

摘　　要：在资源紧缺背景下,采用廉价废弃物发酵制备生物己酸已成为新近研究热点,然而"低产"和"高成本"的技术瓶颈限制了生物己酸的工业应用。针对己酸发酵新近研究,对廉价废弃物的己酸转化进行了综述。Clostridium kluyveri是目前研究最多的己酸菌,它主要以乙醇、乙酸和丁酸为底物,通过2个反向β氧化循环实现碳链增长生成己酸。混菌发酵技术、关键环境因子(如电子供体和电子受体浓度等)调控和抑制因素解除,是提高生物己酸产量的重要手段。采用廉价底物能够降低生物己酸的原料成本、提高己酸经济性,是未来己酸发酵的发展方向。食品废弃物能量密度高、排放量大,用于生物己酸发酵具有广阔的前景。Biocaproate production using cost-effective wastes via anaerobic fermentation becomes a research hot topic due to resource shortage.However,low productivity of caproate limits its wide application in industry.Recent advances of biocaproate production via anaerobic fermentation and the application of cost-effective substrates are reviewed.Clostridium kluyveri is the most common strain used for caproate production,where ethanol,acetate,and butyrate are used as substrates for caproate biosynthesis through two reverseβoxidation cycles to achieve chain elongation.Coculture fermentation,regulation of key environmental factors(electron donor and acceptor concentrations)and alleviation of the inhibitory effects are important methods for improving caproate production.The application of cost-effective substrates reduces production cost,which becomes trends in the future.Food waste is an ideal substrate for caproate production due to its high energy density and productivity.

关 键 词：己酸 乙醇 Clostridium kluyveri 食品废弃物 混菌发酵 

分 类 号：TK6[动力工程及工程热物理—生物能] X712[环境科学与工程—环境工程]