Roles of AKR1C3 in malignancy  

作　　者：Xin-Zhu Xiao Li-Ying Lin Ming-Kai Zhuang Can-Mei Zhong Feng-Lin Chen 

机构地区：[1]Department of Gastroenterology,Union Hospital of Fujian Medical University,Fuzhou,Fujian 350001,China

出　　处：《Chinese Medical Journal》2021年第9期1052-1054,共3页中华医学杂志（英文版）

基　　金：supported by the Medical Innovation Project of Fujian Province(No.2019-CX-14);the Joint Funds for the Innovation of Science and Technology,Fujian province(No.2019Y9083);the Fujian Medical University Cancer Center and the Key Clinical Specialty Discipline Construction Program of Fujian,China(No.Min Wei Ke Jiao 2012 No.149)。

摘　　要：The superfamily of aldo-keto reductases(AKRs)is composed of over 190 members and can be classified into 16 different families(visit www.med.upenn.edu/akr).AKR1C3(C3 subtype of aldosterone reductase family 1)refers to the first AKR in family 1,subfamily C,and is encoded by the AKR1C3 gene.AKR1C3 was first cloned and expressed from a human prostate cDNA library.This protein is a soluble monomeric NADP(H)(nicotinamideadenine dinucleotide phosphate or reduced form of nicotinamide adenine dinucleotide phosphate)dependent oxidoreductase.

关 键 词：DINUCLEOTIDE AKR1C3 ADENINE 

分 类 号：R730.2[医药卫生—肿瘤]