Lactate-avid regulatory T cells:metabolic plasticity controls immunosuppression in tumour microenvironment  

作　　者：Gabriele Multhoff Peter Vaupel 

机构地区：[1]Radiation Immuno-Oncology Project Group,TranslaTUM–Central Institute for Translational Cancer Research,Klinikum rechts der Isar,TU München,Munich,Germany [2]Department of Radiation Oncology,Klinikum rechts der Isar,TU München,Munich,Germany [3]Department of Radiooncology and Radiotherapy,Tumour Pathophysiology Group,University Medical Centre Mainz,Mainz,Germany

出　　处：《Signal Transduction and Targeted Therapy》2021年第5期1418-1419,共2页信号转导与靶向治疗（英文）

基　　金：Open Access funding enabled and organized by Projekt DEAL.

摘　　要：The excellent article by Watson et al.1 points the way ahead to the important role of lactic acid/lactate-anion and glucose on the immunosuppressive activity of lactate-and glucose-affine metabolically distinct subsets of regulatory T(Treg)cells within the tumour microenvironment(TME)(Fig.1).

关 键 词：TUMOUR al. MICROENVIRONMENT 

分 类 号：R730.51[医药卫生—肿瘤]