Circulating plasma cells(CPCs)in patients of plasma cell neoplasm have been an area of intense research in recent decades.Circulating tumor plasma cells(CTPCs)might represent a sub-clone of tumor cells that have exite...
Cholangiocarcinoma(CCA)is a highly aggressive and heterogeneous malignancy arising from the epithelial cells of the biliary tract.The limitations of the current methods in the diagnosis of CCA highlight the urgent nee...
supported by the National Key R&D National Key Research and Development Program of China(grant number 2023YFC2705803).
INTRODUCTION Gestational trophoblastic neoplasia(GTN)is a group of malignant tumours caused by the abnormal proliferation of placental trophoblastic cells.It primarily includes invasive mole,choriocarcinoma,placental ...
In this article,we comment on the work published by Huang et al,which explores the mechanisms by which Calculus bovis(CB)modulates the liver cancer immune microenvironment via the Wnt/β-catenin signalling pathway.The...
supported by the National Natural Science Foundation of China(82274103,82074272,China);the Young Scientists Fund of the National Natural Science Foundation of China(82305039,China);Program of Shanghai Academic Research Leader(21XD1403400,China);Program of National Key Research and Development(2023YFC3404103,China);the Cooperation Program of the Xuhui District Medical College with Enterprisess(23XHYD-24,China);the Science and Technology Commission of Shanghai Municipality(23S21900200,China)。
Tumor immunotherapy characterized by its high specificity and minimal side effects has achieved revolutionary progress in the field of cancer treatment.However,the complex mechanisms of tumor immune microenvironment(T...
BACKGROUND Hyperplastic polyps,which represent 30%-93%of all gastric epithelial polyps,are the second most common type of gastric polyps after fundic gland polyps.They were previously considered to have no risk of neo...
German translational cancer network(DKTK),the Frankfurt Cancer Institute(FCI);German Cancer Aid(Krebshilfe)grant TACTIC and the SFB1430(Molecular Mechanisms of Cell State Transitions)。
A recent study published in Nature by Radko-Juettner and colleagues reports an unexpected mutant-specific synthetic lethality in which the E3 protein ubiquitin ligase DCAF5 specifically degrades mutant but not wild-ty...
Support by German Cancer Aid grants 70112720 and 70113167 to S.R.is gratefully acknowledged.
In a recent paper published in Nature Medicine,Bojmar et al.describe an elaborate effort toward predicting the metastatic progress of pancreatic ductal adenocarcinoma(PDAC)after primary tumour resection.1 Instead of i...
supported by the National Natural Science Foundation of China(No.82001965).
Cancer remains one of the leading causes of death worldwide,and tumour metastasis is responsible for more than 90%of cancer deaths.1,2 Bone is recognised as the most common site for metastasis of numerous malignancies...
We report on an unusual case presenting with a cardiac pseudo-tumour on echocardiogram, which corresponded to a large soft tissue mural thickening around the mid-right coronary artery. There were similar but not as th...