植源肽对啮齿动物神经退行性疾病的影响  

Effect of Plant-derived Peptide on Neurodegenerative Diseases in Rodents

作　　者：蔡洁[1] 崔校基 唐柳欢 陈忠旭 梁盈[1] Cai Jie;Cui Xiaoji;Tang Liuhuan;Chen Zhongxu;Liang Ying(Center South University of Forestry and Technology,National Engineering Laboratory of Rice and By-product Deep Processing,Changsha 410004)

机构地区：[1]中南林业科技大学稻谷及副产物深加工国家工程实验室,长沙410004

出　　处：《中国食品学报》2021年第7期360-370,共11页Journal of Chinese Institute Of Food Science and Technology

基　　金：湖南省自然科学基金面上项目(2020JJ4138);国家自然科学基金面上项目(31571874);湖湘青年科技创新人才项目(2016RS3033);湖南省教育厅科学研究项目(18A160)。

摘　　要：神经退行性疾病是世界主要公共卫生问题之一,然而,目前缺乏治疗神经退行性疾病的有效药物,膳食营养干预是目前最受欢迎的干预手段之一。植源肽通过诸多途径在人类健康中发挥重要作用,如抗氧化、抗炎、保护神经系统等。本文综述植源肽对啮齿动物神经退行性疾病的作用机制,并展望其在神经退行性疾病应用中的机遇与挑战。Neurodegenerative disease is one of the major public health problems worldwide,but the treatment of these diseases still lacks effective drugs.It is one of the most popular methods that using dietary nutrition to intervene neurodegenerative disease so far.Plant-derived peptides play a significant role in human health by many ways,such as antioxidation,anti-inflammatory,nervous system protection and so on.This article reviews the mechanism of action of plant source peptides on neurodegenerative diseases in rodents,and outlooks its opportunities and challenges in the treatment application of neurodegenerative diseases.

关 键 词：植源肽 退行性疾病 啮齿动物 

分 类 号：R741[医药卫生—神经病学与精神病学]