CCRK-a hub for liver metastasis and cancer  

作　　者：Jie-Ting Low Guan-Ling Lin Michael W.Y.Chan 

机构地区：[1]Department of Biomedical Sciences,National Chung Cheng University,Min-Hsiung,Chia-Yi,Taiwan,China [2]Epigenomics and Human Disease Research Center,National Chung Cheng University,Min-Hsiung,Chia-Yi,Taiwan,China [3]Center for Innovative Research on Aging Society(CIRAS),National Chung Cheng University,Min-Hsiung,Chia-Yi,Taiwan,China

出　　处：《Cellular & Molecular Immunology》2021年第5期1341-1342,共2页中国免疫学杂志（英文版）

基　　金：supported by a grant from the Ministry of Science and Technology(MOST 108-2314-B-194-003-MY2).

摘　　要：The liver is one of the most common sites for cancer metastasis,which leads to secondary hepatic malignancies.Almost all solid tumors,such as melanoma,breast cancer,gastric cancer,colorectal cancer,and lung cancer,metastasize to the liver.1,2 Overall,20–25%of colorectal cancer patients may eventually develop liver metastases(also known as CRC liver metastases).3 In addition to some common occurrence of liver metastasis in colorectal cancer,the liver is also one of the predominant metastatic sites for melanoma,including cutaneous and ocular melanoma.2 Thus,an understanding of the mechanism of liver metastasis is urgently needed for the development of novel strategies to prolong overall survival for patients with liver metastases.

关 键 词：METASTASIS CANCER COLORECTAL 

分 类 号：R735.7[医药卫生—肿瘤]