壳寡糖功能特性研究进展  

Research Progress on the Functional Characteristics of Chitooligosaccharides

作　　者：孙晨松 王硕 王一迪 董德刚[2] 徐贤柱[1] 蔡险峰[1] 王曼莹[1] 游清徽[1] SUN Chensong;WANG Shuo;WANG Yidi;DONG Degang;XU Xianzhu;CAI Xianfeng;WANG Manying;YOU Qinghui(College of Life Sciences,Jiangxi Normal University,Nanchang 330022,China;College of Life Sciences,Jiangxi University of Traditional Chinese Medicine,Nanchang 330004,China)

机构地区：[1]江西师范大学生命科学学院,江西南昌330022 [2]江西中医药大学基础医学院,江西南昌330004

出　　处：《食品工业科技》2021年第16期438-446,共9页Science and Technology of Food Industry

基　　金：国家科技重大专项子课题(2018ZX09721002-008);国家自然科学基金项目(41967055)。

摘　　要：壳寡糖是一种2~10个氨基葡萄糖以β-1,4糖苷键连接组成的碱性天然寡糖,通常由壳聚糖经化学、物理或酶法水解制备。壳寡糖具备多种重要的生物活性,如防治与代谢相关的糖尿病、高血脂症,抗肿瘤,缓解退行性疾病阿尔兹海默病、骨关节炎,提高免疫力等。已有许多研究者对其功能特性进行前期探索,获取大量有效数据,因此壳寡糖具备广阔的开发前景。本文专门对近年来壳寡糖功能特性研究及作用机理进行了论述,并分析了目前壳寡糖研究中存在的问题,以期为后续深入研究提供参考依据。Chitooligosaccharides are natural oligosaccharides composed byβ-1,4-linked homopolymer of 2~10 units of glucosamine(GlcN),and usually prepared by chemical,physical or enzymatic hydrolysis of chitosan.Chitooligosaccharides have many important biological activities,such as preventing and treating metabolic related diabetes,hyperlipidemia,antitumor,alleviating degenerative diseases such as Alzheimer’s disease,osteoarthritis,and improving immunity.Many researchers have conducted preliminary explorations on the functional characteristics of chitooligosaccharides and obtained a large amount of effective data,so it has broad development prospects.In this paper,the research on the functional characteristics and mechanism of chitooligosaccharides in recent years are reviewed,and the existing problems in the research are analyzed,so as to provide reference for the further research.

关 键 词：壳寡糖 功能特性 代谢疾病 退行性疾病 作用机理 

分 类 号：TS201.2[轻工技术与工程—食品科学]