Overgrowth of Lactobacillus in gastric cancer  

作　　者：Zhi-Peng Li Ju-Xin Liu Lin-Lin Lu Li-Li Wang Lin Xu Zong-Hao Guo Quan-Jiang Dong 

机构地区：[1]Department of Gastroenterology and Central Laboratories,Qingdao Municipal Hospital,Qingdao University,Qingdao 266071,Shandong Province,China [2]Clinical Laboratories,Qingdao Municipal Hospital,Qingdao 266071,Shandong Province,China [3]Department of Clinical Medicine,Jining Medical University,Jining 272000,Shandong Province,China

出　　处：《World Journal of Gastrointestinal Oncology》2021年第9期1099-1108,共10页世界胃肠肿瘤学杂志（英文版）（电子版）

基　　金：Supported by The National Natural Science Foundation of China,No.31870777.

摘　　要：Dysbiosis of the gastric microbiome is involved in the development of gastric cancer(GC).A number of studies have demonstrated an increase in the relative abundance of Lactobacillus in GC.In this review,we present data that support the overgrowth of Lactobacillus in GC from studies on molecular and bacterial culture of the gastric microbiome,discuss the heterogenic effects of Lactobacillus on the health of human stomach,and explore the potential roles of the overgrowth of Lactobacillus in gastric carcinogenesis.Further studies are required to examine the association between Lactobacillus and GC at strain and species levels,which would facilitate to elucidate its role in the carcinogenic process.

关 键 词：LACTOBACILLUS Gastric cancer GASTRITIS MICROBIOME Next generation sequencing 

分 类 号：R735.2[医药卫生—肿瘤]