营养对新型冠状病毒致肠肺轴损伤的修复  

THE ROLE OF NUTRITION IN GUT-LUNG AXIS INJURY CAUSED BY CORONAVIRUS

作　　者：于海宁[1] 秦秀媛 沈生荣[2] YU Hai-ning;QIN Xiu-yuan;SHEN Sheng-rong(Zhejiang University of Technology,Hangzhou 310014;Zhejiang University,Hangzhou 310058,China)

机构地区：[1]浙江工业大学,杭州310014 [2]浙江大学,杭州310058

出　　处：《营养学报》2021年第3期298-301,共4页Acta Nutrimenta Sinica

摘　　要：肠道作为人体最大的免疫系统,维持着机体70%的免疫力,微生物群是致病菌感染的屏障。营养不良和免疫功能紊乱都可能破坏这种屏障功能。受损的粘膜屏障在病毒攻击下又会进一步导致微生物易位和免疫敏化,并使得营养物质吸收障碍,经由肠肺轴,对肺部疾病造成恶化循环。本文根据肠肺轴理论,从营养、免疫及肠道微生态平衡角度探讨新型冠状病毒肺炎的营养治疗思路。As the body’s largest immune system,the intestine maintains 70%of the immunity.The microbiota constitute a barrier to the infection by pathogenic bacteria.Malnutrition and immune dysfunction may disrupt this barrier function.The damaged mucosal barrier will consequently lead to microbial translocation and immune sensitization in case of virus attack,posing an obstacle to nutrient absorption and causing a cycle of deterioration to the lung through the gut-lung axis.Based on the theory of the gut-lung axis,this article discusses how to treat Covid-19 infection in terms of nutrition,immunity and intestinal microecological balance.

关 键 词：营养 新型冠状病毒 肠肺轴 肠道菌群 免疫调节 

分 类 号：R151.41[医药卫生—营养与食品卫生学]