Astrocyte,reactive astrocytes and self-regulative apoptosis in the neuroinflammation  

作　　者：Liang-Wei Chen 

机构地区：[1]Institute of Neurosciences,Department of Neurobiology and Collaborative Innovation Center for Brain Science,The Fourth Military Medical University,Xi’an 710032,Shaanxi,China

出　　处：《Neuroimmunology and Neuroinflammation》2016年第1期167-169,共3页神经免疫与神经炎症（英文版）

基　　金：Supported by grants from the National Natural Science Foundation of China(31371374);the National Basic Research Program(2012CB525002).

摘　　要：Astrocyte,one of the most abundant glial cell types,actively functions in stabilizing neural circuits and synaptic transmission in the central nervous system(CNS).Astrocytes not only provide metabolic and trophic supports to various CNS neurons and but also actively work in assisting synaptic transmission and plasticity.A line of growing evidences have documented that astrocytes present as an essential coordinatorin neural circuit function.[1]Firstly,calcium signaling or calcium wave calcium(Ca^(2+))between neighboring astrocytes contribute to establishment of a huge astrocytic glial network by gap-junctions,which has updated the understanding of astrocyte function in CNS,and led to an idea that astrocytes are powerful regulators of neuronal spiking.

关 键 词：ASTROCYTES INFLAMMATION NEURAL 

分 类 号：R74[医药卫生—神经病学与精神病学]