Itraconazole therapy for infant hemangioma:Two case reports  

作　　者：Zhe Liu Sha Lv Shuang Wang Sheng-Ming Qu Gui-Yun Zhang Yi-Tong Lin Lei Yang Fu-Qiu Li 

机构地区：[1]Department of Dermatology,The Second Hospital of Jilin University,Changchun 130041,Jilin Province,China

出　　处：《World Journal of Clinical Cases》2021年第28期8579-8586,共8页世界临床病例杂志

摘　　要：BACKGROUND Infantile hemangiomas(IHs)are the most common childhood benign tumors,showing distinctive progression characteristics and outcomes.Due to the high demand for aesthetics among parents of IH babies,early intervention is critical in some cases.β-Adrenergic blockers and corticosteroids are first-line medications for IHs,while itraconazole,an antifungal medicine,has shown positive results in recent years.CASE SUMMARY In the present study,itraconazole was applied to treat two IH cases.The therapeutic course lasted 80-90 d,during which the visible lesion faded by more than 90%.Moreover,no obvious side effects were reported,and the compliance of the baby and parents was desirable.CONCLUSION Although these outcomes further support itraconazole as an effective therapeutic choice for IHs,large-scale clinical and basic studies are still warranted to improve further treatment.

关 键 词：INFANT HEMANGIOMAS THERAPEUTICS ITRACONAZOLE ORAL Case report 

分 类 号：R732.2[医药卫生—肿瘤]