ITRACONAZOLE

作品数:42被引量:68H指数:5
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相关领域:医药卫生更多>>
相关作者:冯丽娟刘伟李若瑜谭静文罗晓更多>>
相关机构:北京大学第一医院北京大学首都医科大学附属北京友谊医院湖北医药学院更多>>
相关期刊:《Journal of Pharmaceutical Analysis》《实用休克杂志(中英文)》《Open Journal of Obstetrics and Gynecology》《Open Journal of Medical Microbiology》更多>>
相关基金:国家自然科学基金泰国研究基金教育部“新世纪优秀人才支持计划”国家重点基础研究发展计划更多>>
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Evaluating the Effects of Crystallinity on Drug Release Behaviour in Itraconazole- or Miconazole-Loaded PLGA Microparticles Prepared Using a Co-Grinding Method
《Pharmacology & Pharmacy》2023年第9期348-362,共15页Kazuhiro Matsuura Honami Kojima Miyako Yoshida Takahiro Uchida 
This study aimed to prepare and characterize itraconazole (ITCZ)- or miconazole (MCZ)-loaded poly (lactide-co-glycolide) (PLGA) microparticles (MP) using a co-grinding method with ball milling, which is a solvent-free...
关键词:Co-Grinding Method Ball Milling Poly (Lactide-co-Glycolide) ITRACONAZOLE MICONAZOLE Amorphization 
Intravenous-oral itraconazole versus oral posaconazole in preventing invasive fungal diseases for acute leukemia patients
《Blood Science》2023年第2期106-110,共5页Li Liua Xiaolei Peia Runzhi Maa Yi Hea Rongli Zhanga Jialin Weia Qiaoling Maa Weihua Zhaia Aiming Pang Erlie Jiang Mingzhe Han Donglin Yang Sizhou Feng 
the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(CIFMS)[2021-I2M-1-017]and[2021-I2M-C&T-B-080];Haihe Laboratory of Cell Ecosystem Innovation Fund[HH22KYZX0036].
Invasive fungal diseases(IFDs)are major and lethal infectious complications for patients with neutropenia after chemotherapy.Prophylaxis with intravenous and oral suspended itraconazole(200 mg Q12h intravenously×2 da...
关键词:Acute leukemia Antifungal prophylaxis Invasive fungal disease ITRACONAZOLE POSACONAZOLE 
Pharmacokinetics/Pharmacodynamics study of Fixtral SB as compared to supra bioavailable itraconazole and conventional itraconazole
《World Journal of Pharmacology》2023年第1期1-11,共11页Syed Mujtaba Hussain Naqvi Monil Yogesh Neena Gala Snehal Muchhala Anand Arumugam Dhananjay Panigrahi Dipak Patil Rahul Rathod Amey Mane 
BACKGROUND Itraconazole is a broad-spectrum triazole antifungal inhibiting fungal growth by inhibiting ergosterol synthesis and exhibits a nonlinear pharmacokinetic profile.Erratic absorption pattern with wide fluctua...
关键词:Supra-Bioavailable itraconazole Conventional itraconazole Oral bioavailability PHARMACODYNAMICS EFFICACY Adverse events 
Atypical Cutaneous Leishmaniasis by Leishmania Mexicana: A Case Report with Dermoscopic, Histopathological and Molecular Study
《Advances in Microbiology》2022年第11期597-602,共6页Marina Romero-Navarrete Lucio Vera-Cabrera Roberto Arenas María Elisa Vega-Memije Aureliano Castillo-Solana 
Cutaneous leishmaniasis is a neglected tropical skin endemic disease, with worldwide distribution. By 2020 in the Americas, Mexico was in 12th place with 11 states reporting new cases. Molecular biology with different...
关键词:Atypical Cutaneous Leishmaniasis Neglected Tropical Skin Diseases Lutzomyia Leishmania mexicana ITRACONAZOLE 
Itraconazole通过靶向C1GALT1抑制胃癌细胞侵袭和转移
《湖北医药学院学报》2022年第5期441-446,F0002,F0003,共8页董晓霞 刘玉凤 俞靖蕾 张佳丽 孙碧瑶 李知远 沈力 
国家自然科学基金项目(81902494)。
目的:探讨伊曲康唑(Itraconazole)对胃癌细胞侵袭转移的影响及机制。方法:体外培养胃癌AGS和MKN45细胞,Itraconazole处理后采用CCK-8和克隆形成测定细胞增殖,Transwell和划痕实验观察细胞侵袭迁移,流式细胞术检测细胞周期和凋亡。随后,...
关键词:伊曲康唑 胃癌 C1GALT1 侵袭 转移 
Itraconazole and rifampicin, as CYP3A modulators but not P-gp modulators, affect the pharmacokinetics of almonertinib and active metabolite HAS-719 in healthy volunteers被引量:4
《Acta Pharmacologica Sinica》2022年第4期1082-1090,共9页Lu Liu Wei Li Le Yang Zi-tao Guo Hao Xue Ning-jie Xie Xiao-yan Chen 
This work was supported by the National Natural Science Foundation of China(Grant 82073924)。
Almonertinib is a novel third-generation EGFR tyrosine kinase inhibitor. It is mainly metabolized by CYP3A in vitro, and N-desmethylated almonertinib (HAS-719) is the major active metabolite in human plasma. In this s...
关键词:almonertinib itraconazole RIFAMPICIN drug metabolism drug interaction CYP3A P-GP PHARMACOKINETICS 
Disseminated Blastomycosis during Pregnancy at 11 Weeks Gestation
《Open Journal of Obstetrics and Gynecology》2022年第2期118-123,共6页Caroline E. Dillon Paula A. McKenzie 
Blastomyces dermatitidis is a dimorphic fungus that typically causes disease in immunocompromised hosts, but can affect immunocompetent patients as well. Here we present a case of disseminated blastomycosis in a pregn...
关键词:BLASTOMYCES ITRACONAZOLE AMPHOTERICIN Antifungal 
Itraconazole therapy for infant hemangioma:Two case reports被引量:1
《World Journal of Clinical Cases》2021年第28期8579-8586,共8页Zhe Liu Sha Lv Shuang Wang Sheng-Ming Qu Gui-Yun Zhang Yi-Tong Lin Lei Yang Fu-Qiu Li 
BACKGROUND Infantile hemangiomas(IHs)are the most common childhood benign tumors,showing distinctive progression characteristics and outcomes.Due to the high demand for aesthetics among parents of IH babies,early inte...
关键词:INFANT HEMANGIOMAS THERAPEUTICS ITRACONAZOLE ORAL Case report 
Tinea capitis caused by Microsporum Canis in a child:a case report
《实用休克杂志(中英文)》2021年第3期190-192,共3页Shi Ting Zeng Ling Zheng Shujuan Liang Jian Zhang Xiao Xie Liangyi 
We report a tinea capitis caused by Microsporun Canis.A 6-year-old girl who had a history contact with dogs and cats in rural area.The girl suffered from scalp mass,pustules and itching for 2 months.There were two rou...
关键词:Microsporun Canis Tinea capitis Macroconidium ITRACONAZOLE KETOCONAZOLE 
Metabonomic analysis of plasma biochemical changes in pyrexia rats after treatment with Gegenqinlian decoction,aspirin and itraconazole by UHPLC-FT-ICR-MS被引量:6
《Journal of Pharmaceutical Analysis》2020年第6期581-587,共7页Ting Liu Ruiyun Li Yue Cui Zhiguo Yu Yunli Zhao 
the Natural Science Foundation of China(NO.81573629)。
A metabonomic approach involving an ultrahigh-performance liquid chromatography combined with Fourier transform ion cyclotron resonance mass spectrometry(UHPLC-FT-ICR-MS)was used to investigate the changes in the endo...
关键词:Gegenqinlian decoction ASPIRIN ITRACONAZOLE PYREXIA UHPLC-FT-ICR-MS Metabonomic 
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