POSACONAZOLE

作品数：23被引量：31H指数：4
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相关领域：医药卫生更多>>
相关作者：胡春刘晓平更多>>
相关机构：沈阳药科大学北京协和医学院重庆医科大学更多>>
相关期刊：《Chinese Medical Journal》《Blood Science》《国外药讯》《世界临床药物》更多>>
相关基金：国家自然科学基金更多>>
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Intravenous-oral itraconazole versus oral posaconazole in preventing invasive fungal diseases for acute leukemia patients
《Blood Science》2023年第2期106-110,共5页Li Liua Xiaolei Peia Runzhi Maa Yi Hea Rongli Zhanga Jialin Weia Qiaoling Maa Weihua Zhaia Aiming Pang Erlie Jiang Mingzhe Han Donglin Yang Sizhou Feng 
the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(CIFMS)[2021-I2M-1-017]and[2021-I2M-C&T-B-080];Haihe Laboratory of Cell Ecosystem Innovation Fund[HH22KYZX0036].
Invasive fungal diseases(IFDs)are major and lethal infectious complications for patients with neutropenia after chemotherapy.Prophylaxis with intravenous and oral suspended itraconazole(200 mg Q12h intravenously×2 da...
关键词：Acute leukemia Antifungal prophylaxis Invasive fungal disease ITRACONAZOLE POSACONAZOLE 
Complicated multiple organ infection of Purpureocillium lilacinum and varicella-zoster virus infection in a patient with Evans’ syndrome
《Blood Science》2022年第2期89-92,共4页Xiangrong Hu Li Zhang Qingsong Lin Fengkui Zhang Xin Zhao 
This study was supported by Grant 18JCYBJC41200 of Tianjin Municipal Science and Technology Commission Grant.
Purpureocillium lilacinum(P lilacinum)is a rare pathogenic fungus,which mainly involves immunocompromised individuals.Here,we report a case of complicated multiple-organ infections involving skin,lungs,and spleen in a...
关键词：Evans’syndrome Fungal infection POSACONAZOLE Purpureocillium lilacinum Varicella-zoster virus 
Use of bronchoscopy-guided treatment and oral posaconazole to treat pulmonary mucormycosis:a case report and literature review
《Infectious Diseases Research》2021年第4期1-5,共5页Peng-Cheng Zhou Wei Yu 
funded by the 2020 Xinglin Scholars Scientific Research Promotion Plan of Chengdu University of Traditional Chinese Medicine(QNXZ2020007);the Hundred Talents Plan Project of Hospital of Chengdu University of Traditional Chinese Medicine(20-Q07).
Background:Pulmonary mucormycosis(PM)is rare condition,which is difficult to diagnose and has a high mortality rate.Currently,there is a lack of effective drugs,with few side effects,to treat PM.There have been a few ...
关键词：Pulmonary mucormycosis BRONCHOSCOPY POSACONAZOLE liposomal amphotericin B 
Successful treatment of cutaneous mucormycosis disseminated from pulmonary mucormycosis with liposomal amphotericin B and posaconazole被引量：5
《Chinese Medical Journal》2020年第14期1747-1748,共2页Xiao-Lan Ding Hou-Min Li Juan Du 
To the Editor:A 52-year-old man presented with fever and a painful ulcer on the right thigh for 10 days.The patient had acute lymphoblastic leukemia for 2 years.Two months ago,the patient developed cough and expectora...
关键词：DIAGNOSIS FEVER PULMONARY 
Pharmacokinetic/Pharmacodynamic Analysis the Probability of Target Attainment of Posaconazole against <i>Mucorales</i>Species in Patients with Mucormycosis
《Pharmacology & Pharmacy》2020年第5期71-78,共8页Ying Wang Jingyi Zhao Yinhui Yao Junhui Hu Jiuli Hu Xu Xiao Yanwu Zhao 
The objective of this study was to investigate the probability of target attainment of various posaconazole dosing regimens against Mucorales species in patients with mucormycosis. According to pharmacokinetic/pharmac...
关键词：Mote Carlo Simulation POSACONAZOLE MUCORALES MUCORMYCOSIS 
Analysis of Pharmacokinetic/Pharmacodynamic Parameters and Dosage Regimen of Posaconazole against <i>Candida</i>spp. and <i>Aspergillus</i>spp. Using Monte Carlo Simulation被引量：1
《Pharmacology & Pharmacy》2020年第1期17-28,共12页Ying Wang Jingyi Zhao Junhui Hu Xinhong Zhao Yinhui Yao 
Invasive fungal infections (IFI) have recently become increasingly more prevalent, resulting in an increased risk of morbidity and mortality. Both Candida spp. and Aspergillus spp. are major causes of IFI. In this stu...
关键词：POSACONAZOLE Monte Carlo Simulation CANDIDA spp. ASPERGILLUS spp. Pharmacokinetics/Pharmacodynamics 
Clinical characteristics and prognoses of pulmonary mucormycosis in four children被引量：2
《Pediatric Investigation》2019年第4期223-227,共5页Siyuan Guo Hui Liu Xiaolei Tang Haiming Yang 
Importance:Pulmonary mucormycosis is life threatening and carries a poor prognosis.Identification of factors that improve prognosis is urgently necessary.Objective:To analyze the clinical features and outcomes of pulm...
关键词：PULMONARY MUCORMYCOSIS LIPOSOMAL AMPHOTERICIN B POSACONAZOLE PROGNOSIS 
Optimized combinations of statins and azoles against Acanthamoeba trophozoites and cysts in vitro
《Asian Pacific Journal of Tropical Medicine》2019年第6期283-287,共5页Ines Sifaoui Carmen M Martín-Navarro Atteneri López-Arencibia María Reyes-Batlle Basilio Valladares JoséE.Pinero Sutherland K Maciver Jacob Lorenzo-Morales 
supported by the grants Red de Investigation Colaborativa en Enfermedades Tropicales RICET(project no.RD16/0027/0001 of the programme of Redes Temáticas de Investigación Cooperativa,FIS),Spanish Ministry of Health,Madrid,Spain;PI13/00490“Protozoosis Emergentes por Amebas de Vida Libre:Aislamiento,Caracterización,Nuevas Aproximaciones Terapéuticas y Traslación Clínica de los Resultados”from the Instituto de Salud Carlos III.IS;supported by the Agustín de Betancourt Programme;supported by Ayudas Plan Propio de la Universidad de La Laguna 2018(proyectos puente I+D+i);supported by PI18/01380 from Instituto de Salud Carlos III and FEDER,Spain and CTQ2014-55888-C03-01/R(MINECO).MRB:RICET[RD16/0027/0001 project,from Programa Redes Temáticas de Investigación Cooperativa,FIS(Ministerio Español de Salud,Madrid,Spain).
Objective: To evaluate the combination of several statins(atorvastatin, fluvastatin and simvastatin) and azoles(voriconazole, posaconazole and itraconazole) against Acanthamoeba spp. Methods: The efficiency of the dif...
关键词：Keratitis VORICONAZOLE POSACONAZOLE Atorvastatin FLUVASTATIN Simvastatin 
Posaconazole-associated severe hyperbilirubinemia in acute myeloid leukemia following chemotherapy: A case report被引量：6
《World Journal of Clinical Cases》2018年第16期1206-1209,共4页Zai-Wei Song Yu-Chen Pan Zhen-Cheng Huang Wen-Xi Liu Rong-Sheng Zhao Hong-Mei Jing Fei Dong 
BACKGROUND Posaconazole is a widely used azole antifungal agent, and posaconazole-associated severe hyperbilirubinemia is usually rare in clinical practice. We herein report a 58-year-old male with acute myeloid leuke...
关键词：POSACONAZOLE HYPERBILIRUBINEMIA Liver INJURY Acute MYELOID LEUKEMIA Case report 
Validated Gradient Stability Indicating UPLC Method for the Determination of Related Substances of Posaconazole in Bulk Drug
《American Journal of Analytical Chemistry》2015年第12期965-976,共12页Vadlamanu Durga Prasad Vanga Ranga Reddy Pasula Aparna 
A stability-indicating UPLC method has been developed and validated for the determination of related substances of Posaconazole with its four related substances (Hydroxytriazole, Tosylated compound, Deshydroxy posacon...
关键词：POSACONAZOLE Hydroxytriazole Tosylated Deshydroxy POSACONAZOLE Benzylated POSACONAZOLE STABILITY-INDICATING ICH Guidelines UPLC 
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