儿童孤独症合并癫痫的脑电图120例特征  

Analysis of electroencephalogram features in 120 children with autism combined with epilepsy

作　　者：杜雅坤[1] 郑华城[1] 陈芳[1] 李宝广[1] 孙晨博 孙素真[1] Du Yakun;ZHeng Huacheng;CHen Fang;Li Baoguang;Sun Chenbo;Sun Suzhen(Department of Neurology,the Hebei Children’s Hospital,Shijiazhuang 050031,China)

机构地区：[1]河北省儿童医院神经内科,石家庄050031

出　　处：《脑与神经疾病杂志》2021年第11期675-678,共4页Journal of Brain and Nervous Diseases

基　　金：河北省卫计委2017年医学课题研究重点课题计划(20170397)。

摘　　要：目的分析儿童孤独症(autism)合并癫痫的临床脑电图(electroencephalogram,EEG)特征。方法对120例儿童孤独症合并癫痫发作的EEG特征进行回顾性分析。结果孤独症合并癫痫患儿中,以局灶性发作(83.3%)最为常见,EEG放电最常出现在部位是额区(40%)和颞区(30%)。患儿的智力水平与发作间期癫痫样放电指数(Interictal epileptiform activity,IEA)呈负相关(r=-0.7361,P<0.0001)。结论EEG作为评估儿童孤独症合并癫痫脑功能的方法,在疾病的诊疗中有着很高的应用价值。Objective To analyze the clinical electroencephalogram(EEG)features in children with autism combined with epilepsy.Methods The EEG features of 120 children with autism combined with seizures were analyzed retrospectively.Results Among the children with autism combined with epilepsy,focal seizures(83.3%)are the most common type of seizures,EEG discharges were most common in the frontal region(40%)and temporal area(30%).The intelligence levels of the patients were negatively correlated with the interictal epileptiform activity(r=-0.7361,P<0.0001).Conclusion EEG as a method to evaluate brain function of children in Autism combined with epilepsy,has a high application value in the diagnosis and treatment of disease.

关 键 词：孤独症 癫痫 脑电图 智力水平 认知功能 

分 类 号：R742.1[医药卫生—神经病学与精神病学]