复合营养粉对STZ大鼠的辅助降血糖效果  

Auxiliary hypoglycemic effect of compound nutritional powder on STZ rats

作　　者：生庆海[1] 刘成 潘丽娜 汪家琦 贾艳菊[1] SHENG Qing-hai;LIU Cheng;PAN Li-na;WANG Jia-qi;JIA Yan-ju(College of Bioscience and Bioengineering,Hebei Univercity of Economics and Business,Shijiazhuang,Hebei 050061,China;Ausnutria Dairy〔China〕Co.,Ltd.,Changsha,Hunan 410200,China)

机构地区：[1]河北经贸大学生物科学与工程学院,河北石家庄050061 [2]澳优乳业〔中国〕有限公司,湖南长沙410200

出　　处：《食品与机械》2022年第1期164-167,174,共5页Food and Machinery

基　　金：河北省重点研发项目(编号:20327105D)。

摘　　要：目的:评估复合营养粉对链脲佐菌素(STZ)诱导的2型糖尿病大鼠(STZ大鼠)的辅助降血糖功能。方法:对SD大鼠静脉注射STZ以构建胰岛损伤2型糖尿病模型,按1.68,3.35,6.70 g/kg剂量连续30 d经口灌胃给予复合营养粉,测定空腹血糖及糖耐量指标,考察复合营养素对STZ大鼠的影响。结果:复合营养粉对STZ大鼠的空腹血糖指标、糖耐量指标均为阳性;对STZ大鼠体重无明显影响。结论:复合营养粉对STZ大鼠具有辅助降血糖功能。Objective:This study focuses on evaluating the auxiliary blood glucose-lowering function of self-made compound nutritional powder in type 2 diabetic rats.Methods:SD rats were intravenously injected with STZ to construct a pancreatic islet injury type 2 diabetes model.The compound nutritional powder was given by oral gavage at doses of 1.68,3.35 and 6.70 g/kg for 30 days.Fasting blood glucose and blood glucose were measured after 30 days.Glucose tolerance index to investigate the effect of compound nutrients on STZ rats.Results:The compound nutritional powder was positive for the fasting blood glucose and glucose tolerance indexes of STZ rats;it had no significant effect on the body weight of STZ rats.Conclusion:The compound nutritional powder has an auxiliary function of lowering blood sugar in STZ rats.

关 键 词：复合营养粉 STZ大鼠 高血糖模型 降血糖 

分 类 号：TS201.4[轻工技术与工程—食品科学]