关注先天性眼球震颤基础与治疗研究的新动向  

Pay attention to the new trend of basic and therapeutic research of congenital nystagmus

作　　者：王乐今[1] 苗泽群 Lejin Wang;Zequn Miao(Department of Ophthalmology,Peking University People′s Hospital Eye Diseases and Optometry Institute,Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases,College of Optometry,Peking University Health Science Center,Beijing 100044,China)

机构地区：[1]北京大学人民医院眼科,眼视光中心,眼病与视光医学研究所,视网膜脉络膜疾病诊治研究北京市重点实验室,北京大学医学部眼视光学院,100044

出　　处：《中华眼科医学杂志（电子版）》2021年第6期321-326,共6页Chinese Journal of Ophthalmologic Medicine(Electronic Edition)

基　　金：国家自然科学基金资助项目(81470665)。

摘　　要：先天性眼球震颤是一种眼动功能障碍疾病,其特征是眼球的共轭、不自主、往复和重复运动,常伴发双眼视力损害、视功能障碍及(或)异常头位。此病病因不明、临床表现多样且难以治疗。眼球震颤患者黄斑注视物象在视网膜上移动过快,导致患者视力及运动敏感性下降,同时也给患者带来心理及社会学方面的打击。目前业内对此病的研究集中在手术方式、手术量改进以及遗传学领域。本文中笔者综合国内外的研究进展,对先天性眼球震颤的病因、分类、临床表现及治疗方法进行评述。Congenital nystagmus is an eye movement dysfunction disease,which is characterized by conjugate,involuntary,reciprocating and repetitive movement of the eye,often accompanied by binocular visual impairment,visual dysfunction and/or abnormal head position.The etiology of the disease is unknown,the clinical manifestations are diverse and difficult to treat.The macular fixation image of patients with nystagmus moves too fast on the retina,which leads to the decrease of vision and motor sensitivity,and also brings psychological and sociological constraints to patients.The recent research focuses on the improvement of surgical methods,surgical volume and genetics.The etiology,classification,clinical manifestations and treatment of congenital nystagmus are reviewed.

关 键 词：先天性眼球震颤 遗传学 植入式神经肌肉刺激器 治疗 

分 类 号：R777.46[医药卫生—眼科]