基于分位数回归的睡眠时长对卒中发病风险的影响研究  

Effects of Sleep Duration on Stroke Risk based on Quantile Regression

作　　者：戴璟[1] 王鑫 张雪 杨云娟[2] 郑昆文[3] Dai Jing;Wang Xin;Zhang Xue(Faculty of Management and Economics,Kunming University of Science and Technology(650093),Kunming)

机构地区：[1]昆明理工大学管理与经济学院,650093 [2]云南省疾病预防控制中心 [3]云南省第一人民医院

出　　处：《中国卫生统计》2022年第1期36-39,共4页Chinese Journal of Health Statistics

基　　金：国家自然科学基金(71764014)。

摘　　要：目的分析睡眠时长对卒中发病风险的影响以及在不同风险人群中的影响效应。方法利用中国营养与健康调查2015年数据,通过WLS回归和分位数回归分析睡眠时长对卒中发病风险的影响。结果共纳入研究对象9566人,WLS回归显示睡眠时长不足和过多会分别增加2.7%和2.4%的卒中发病风险;分位数回归显示随着分位数的提高,睡眠时长对卒中发病风险的影响效应也逐渐增大;在低分位数上,睡眠时长不足对卒中发病风险的回归系数都高于睡眠时长过多,在高分位数上,两者的回归系数相同(Q80:β_(1)=β_(4)=3.5,Q90:β_(1)=β_(4)=11.4)。睡眠时长不足和过多分别会对男性增加1.7%和2.1%的卒中发病风险,对女性增加3.6%和2.6%的卒中发病风险,且随着分位数的提高,睡眠不足和睡眠过多对卒中发病风险的影响在男性和女性间的差异逐渐增大。结论每天睡眠时间低于6小时或高于9小时均会增加卒中发病风险,且卒中高危人群发病风险增加高于中低危人群,对女性卒中发病风险的影响高于男性。建议在卒中干预管理中完善睡眠时间的教育,尤其在女性和高危人群管理中,倡导每天7~8小时的睡眠时长。Objective To analyze the effect of sleep duration on stroke risk and its effect in different risk groups.Methods The effects of sleep duration on stroke risk were analyzed by WLS regression and quantile regression using data from the Chinese nutrition and health survey in 2015.Results A total of 9566 subjects were included in the study.WLS regression showed that short and long sleep duration increased the risk of stroke by 2.7%and 2.4%.Quantile regression showed that the effect of sleep duration on stroke risk increased with the increase of quantile.At the low quantiles,the regression coefficients of short sleep duration to the risk of stroke are higher than those of long sleep duration.At the high quantiles,the coefficients are the same(Q80:β_(1)=β_(4)=3.5,Q90:β_(1)=β_(4)=11.4).Short and long sleep duration increased the risk of stroke by 1.7%and 2.1%in men and 3.6%and 2.6%in women,and as the quantile increases,the differences of impact increased gradually between men and women.Conclusion Sleep duration less than 6 hours or more than 9 hours a day increase stroke risk,and stroke risk in high-risk groups is higher than that in medium-risk and low-risk groups.For low-risk and medium-risk groups,more attention should be paid to short sleep duration,while both short and long sleep duration should be avoided for high-risk groups.Short and long sleep duration have a greater impact on the risk of stroke in women than in men.We suggest improving the education of sleep duration in the management of stroke intervention,especially in the management of women and high-risk groups,and advocating the sleep duration of 7~8 hours per day.

关 键 词：分位数回归 卒中风险 睡眠时长 睡眠不足 

分 类 号：R743.3[医药卫生—神经病学与精神病学]