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作 者:Nafiseh Saghafi Elham Abdollahi Mahsa Khajouee
机构地区:[1]Department of Gynecology and Obstetrics,Mashhad University of Medical Sciences,Mashhad,Iran [2]Immunology Research Center,Inflammation and Inflammatory Disease Research Centre,Mashhad University of Medical Sciences,Mashhad,Iran
出 处:《Proceedings of Anticancer Research》2022年第2期1-5,共5页抗癌研究
摘 要:Ovarian malignancies are the most complicated type among all gynecological cancers.Their etiology is yet unknown;however,they are a heterogeneous,rapidly growing,and very fatal group of cancers.Chronic inflammation and angiogenesis appear to have major contributions in the development and progression of ovarian malignancies.Angiogenesis and inflammation are involved in the pathogenesis of ovarian cancer.Vitamin D3(VitD3)has shown to have anti-inflammatory and anti-angiogenic properties in different types of cancers.The anti-inflammatory and anti-angiogenesis effects of VitD3 on ovarian cancer are investigated in this review.
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