Expert consensus on drug treatment of chronic subdural hematoma  

作　　者：Jianning Zhang Chinese Society of Neurosurgery Chinese Medical Association Chinese Neurosurgical Critical Care Specialist Council Collaborational Group of Chinese Neurosurgical Translational and Evidence-based Medicine 

机构地区：[1]Department of Neurosurgery,Tianjin Medical University General Hospital,Tianjin 300052,China [2]Key Laboratory of Post-trauma Neuro-repair and Regeneration in Central Nervous System,Ministry of Education,Tianjin 300052,China [3]Tianjin Key Laboratory of Injuries,Variations and Regeneration of Nervous System,Tianjin 300052,China [4]Tianjin Neurological Institute,Tianjin 300052,China [5]不详

出　　处：《Chinese Neurosurgical Journal》2022年第1期51-59,共9页中华神经外科杂志（英文）

基　　金：supported by grants 81971176,81720108015,and 81971173 from the National Natural Science Foundation of China;19YFZCSY00650,17JCZDJC35900,15ZXLCSY00060,and 15ZXJZSY00040 from the Tianjin Research Program of Advanced Technology.

摘　　要：Chronic subdural hematoma(CSDH)is a chronic space-occupying lesion formed by blood accumulation between arachnoid and dura mater,which is usually formed in the third week after traumatic brain injury.Surgical treatment is usually the first choice for patients with CSDH having a significant space-occupying effect.Most of the patients showed good results of surgical treatment,but still some patients had a postoperative recurrence(the recurrence rate was up to 33%).Because CSDH is often seen in the elderly,patients are weak and have many basic diseases.The risk of surgical treatment is high;serious complications and even death(the death rate is up to 32%)can often occur.The overall good prognosis rate of patients aged more than 90 years is 24%.The drug treatment can provide a safe and effective treatment for elderly patients who are weak,intolerable to surgery,or failed in surgery.Low-dose and long-term use of atorvastatin(20mg/d)is suggested for continuous treatment for at least 8 weeks,while low-dose and short-term use of dexamethasone can improve the therapeutic effect of atorvastatin on CSDH.Patients should undergo CT or MRI scanning at least one time within 2 weeks after the start of drug treatment.

关 键 词：CSDH TREATMENT DRUG DEATH 

分 类 号：R743.3[医药卫生—神经病学与精神病学]