海洋寡糖的生物活性研究进展  

Progress in Understanding the Biological Activities of Marine Oligosaccharides

作　　者：孙慧慧[1] 杨国淞 程伊梦 李昭悦 赵玲[1] 曹荣[1,3] 刘淇 SUN Huihui;YANG Guosong;CHENG Yimeng;LI Zhaoyue;ZHAO Ling;CAO Rong;LIU Qi(Yellow Sea Fisheries Research Institute,Chinese Academy of Fishery Sciences,Qingdao 266071,China;College of Food Science and Engineering,Ocean University of China,Qingdao 266003,China;Laboratory for Marine Drugs and Biological Products,Pilot National Laboratory for Marine Science and Technology(Qingdao),Qingdao 266237,China)

机构地区：[1]中国水产科学研究院黄海水产研究所,山东青岛266071 [2]中国海洋大学食品科学与工程学院,山东青岛266003 [3]青岛海洋科学与技术试点国家实验室海洋药物与生物制品功能实验室,山东青岛266237

出　　处：《食品科学》2022年第13期276-284,共9页Food Science

基　　金：“十三五”国家重点研发计划重点专项(2019YFD0901902);国家自然科学基金青年科学基金项目(31801574);中国水产科学研究院黄海水产研究所基本科研业务费资助项目(20603022021020)。

摘　　要：寡糖是具有2~10个单糖残基通过糖苷键连接起来的直链或含分支链的糖类化合物,对人体健康有诸多益处,还具有甜味剂功能和特性,集营养、保健、食疗于一体。相较于多糖,寡糖还具有生物活性强、利于机体吸收等优点。近年来,海洋来源的寡糖被证明具有多种生物活性,包括抗氧化、抗肿瘤、抗炎、抗菌、抗凝血和提高免疫力等,可以广泛应用于食品、医药、化妆品、农业和水产等领域。本文介绍了4种主要的海洋寡糖,包括几丁寡糖/壳寡糖、褐藻胶寡糖、琼胶寡糖和卡拉胶寡糖,简述其来源、结构特征、各种生物活性及应用,以期为海洋多糖资源的高价值利用及海洋寡糖的深度开发提供参考。Oligosaccharides are linear or branched carbohydrate compounds composed of two to ten monosaccharide residues connected by glycosidic bonds.They have many health benefits,and can function as sweeteners.Oligosaccharides are a combination of nutritiousness,health care,and dietetic therapy.Compared with polysaccharides,oligosaccharides have several advantages,such as stronger biological activity and easier absorption by the body.In recent years,marinederived oligosaccharides have been proven to have a variety of biological activities,such as antioxidant,anti-tumor,anti-inflammatory,antibacterial,anticoagulant,and immunity-enhancing activities.They can be widely used in food,medicine,cosmetics,agriculture,aquatic products,and other fields.This paper introduces four major marine-derived oligosaccharides,including N-acetyl chitooligosaccharide/chitooligosaccharide,alginate oligosaccharides,agarooligosaccharides,and carrageenan oligosaccharides,and presents a brief description of their sources,structural characteristics,various biological activities and applications.It is expected to provide a reference for the high-value utilization of marine polysaccharide resources and the in-depth development of marine oligosaccharides.

关 键 词：海洋寡糖 几丁寡糖/壳寡糖 褐藻胶寡糖 卡拉胶寡糖 琼胶寡糖 

分 类 号：TS254.9[轻工技术与工程—水产品加工及贮藏工程]