基于我国动物性食品中禁限用兽药使用规定的食源性兴奋剂种类浅析  

Analysis of Food-Derived Doping Based on the Regulations on the Use of Veterinary Drugs in Animal-Derived Foods in China

作　　者：李雅琼 耿健强 穆同娜 徐友宣 徐士新[3] 刘新亮[4] 孙蕊 马娇 LI Yaqiong;GENG Jianqiang;MU Tongna;XU Youxuan;XU Shixin;LIU Xinliang;SUN Rui;MA Jiao(Beijing Municipal Center for Food Safety Monitoring and Risk Assessment,Beijing 100094,China;China Anti-Doping Agency,Beijing 100029,China;China Institute of Veterinary Drugs Control,Beijing 100081,China;School of E-Commerce and Logistics,Beijing Technology and Business University,Beijing 100048,China)

机构地区：[1]北京市食品安全监控和风险评估中心,北京100094 [2]中国反兴奋剂中心,北京100029 [3]中国兽药监察所,北京100081 [4]北京工商大学电商与物流学院,北京100048

出　　处：《食品科学》2022年第13期319-326,共8页Food Science

基　　金：北京市科技计划项目(Z191100008619007);“十三五”国家重点研发计划重点专项(2019YFC1606503)。

摘　　要：本文通过对GB 31650—2019《食品安全国家标准食品中兽药最大残留限量》允许使用的兽药、农业农村部第250号等系列公告禁用兽药以及世界反兴奋剂机构(World Anti-Doping Agency,WADA)《WADA禁用清单国际标准(2021年)》中11个大类315种禁用物质和监控程序涉及的物质进行对比分析,运用Python的第三方函数库对比算法,发现《WADA禁用清单国际标准(2021年)》中蛋白同化制剂、β2-激动剂、糖皮质激素类、刺激剂、利尿剂和掩蔽剂以及肽类激素6个大类的33种物质与我国动物性食品兽药使用规定相应种类重合。同时对大型赛事防控食源性兴奋剂种类进行分析比较,发现有蛋白同化制剂、β2-激动剂、β-阻断剂、利尿剂和掩蔽剂、刺激剂、糖皮质激素类6个大类39种药物与WADA禁用药物相同;有蛋白同化制剂、β2-激动剂、利尿剂和掩蔽剂、刺激剂、糖皮质激素类5个大类25种药物与农业农村部禁限用兽药种类相同;与WADA禁用药物和农业农村部禁限用兽药种类均相同的有蛋白同化制剂、β2-激动剂、利尿剂和掩蔽剂、刺激剂、糖皮质激素类5个大类19种兴奋剂。以上分析结果为进一步明确食源性兴奋剂种类及范围提供工作思路,为加强重大体育赛事动物性食品中食源性兴奋剂的防控工作提供参考。In this paper,we analyzed the veterinary drugs allowed for use in accordance with the National Food Safety Standard Maximum Residue Limits for Veterinary Drugs in Foods(GB 31650–2019),the veterinary drugs banned for use in accordance with Announcement No.250 and other serial announcements of the Ministry of Agriculture and Rural Affairs,the 315 banned substances belonging to 11 classes in the 2021 World Anti-Doping Code Prohibited List 2021,and the substances included in the World Anti-Doping Agency(WADA)2021 Monitoring Program.By using the comparison algorithm of Python’s third-party function library,it was found that 33 substances belonging to six categories including anabolic agents,β2-agonists,glucocorticoids,stimulants,diuretics and masking agents,and peptide hormones were identified to coincide with the corresponding types of animal drugs in animal-derived foods in China.At the same time,the types of food-derived doping to be prevented and controlled in large-scale sports competitions were analyzed and compared,revealing that 39 drugs in the six categories of anabolic agents,β2-agonists,β-blockers,diuretics and masking agents,stimulants,and glucocorticoids were consistent with those prohibited by the WADA,25 drugs of anabolic agents,β2-agonists,diuretics and masking agents,stimulants,and glucocorticoids were consistent with those banned and restricted by the Ministry of Agriculture and Rural Affairs. The veterinary drugs prohibited by both the WADA and the Ministry of Agriculture and Rural Affairs included 19 compounds in the five categories anabolic agents, β2-agonists, diuretics and masking agents, stimulants, and glucocorticoids. The above results provide working ideas for further clarifying the types and scope of food-derived doping, and provide a reference for strengthening the prevention and control of food-derived doping in animal foods for major sports events.

关 键 词：动物性食品 禁限用兽药 世界反兴奋剂机构禁用清单 食源性兴奋剂 

分 类 号：TS207.2[轻工技术与工程—食品科学]