New evidence for a role of Bisphenol A in cell integrity.Implications in the human population  

作　　者：RAFAEL MORENO-GÓMEZ-TOLEDANO MARÍA IARENAS ESPERANZA VÉLEZ-VÉLEZ RICARDO J.BOSCH 

机构地区：[1]Universidad de Alcalá,Laboratory of Renal Physiology and Experimental Nephrology,Department of Biological Systems/Physiology,28871,Alcaláde Henares,Spain [2]Universidad de Alcalá,Cell Biology Unit,Department of Biomedicine and Biotechnology,28871,Alcaláde Henares,Spain [3]Jiménez Díaz Foundation,Fundación Jiménez Díaz School of Nursing,Madrid,28040,Spain

出　　处：《BIOCELL》2022年第2期305-308,共4页生物细胞（英文）

基　　金：supported in part by grants from Instituto de Salud Carlos III(PI15/02139)-Fondo Europeo de Desarrollo Regional(FEDER)-.R.Moreno-Gómez-Toledano is recipient of a research contract from CAM(B2017-BMD-3686).

摘　　要：Bisphenol A(BPA)is a xenoestrogen known for its implications for the endocrine systems and several other organs,including the kidneys.Recent renal studies have shown that BPA can induce alterations of the cytoskeleton and cell adhesion mechanisms such as a podocytopathy with proteinuria and hypertension,alterations involved in the progression of renal diseases.These data and the fact that BPA is known to be present in the urine of almost the entire population strongly suggest the critical need to reevaluate BPA exposures considered safe.

关 键 词：Bisphenol A PODOCYTE CYTOSKELETON Cell Adhesion Chronic Renal Diseases DIALYSIS 

分 类 号：R73[医药卫生—肿瘤]