纤细裸藻β-1,3-葡聚糖异养发酵与生理功效的研究进展  

Research progress on heterotrophic fermentation and physiological functions of Euglena gracilisβ-1,3-glucan

作　　者：吕和鑫 贾士儒 柴谦 刘景君 尚波 刘翼飞 LYU Hexin;JIA Shiru;CHAI Qian;LIU Jingjun;SHANG Bo;LIU Yifei(State Key Laboratory of Food Nutrition and Safety,Key Laboratory of Industrial Fermentation Microbiology Ministry of Education,College of Biotechnology,Tianjin University of Science and Technology,Tianjin 300457,China;Shandong Center For Food and Drug Evaluation&Inspection,Jinan 250013,China;Shandong Nameida Biological Technology Co.,Ltd.,Jinan 250132,China;School of Pharmacy,Macao University of Science and Technology,Macao 999078,China)

机构地区：[1]天津科技大学生物工程学院工业发酵微生物教育部重点实验室省部共建食品营养与安全国家重点实验室,天津300457 [2]山东省食品药品审评查验中心,山东济南250013 [3]山东纳美达生物科技有限公司,山东济南250132 [4]澳门科技大学药学院,中国澳门999078

出　　处：《中国酿造》2022年第8期18-24,共7页China Brewing

基　　金：企业委托技术开发项目(2100040080)。

摘　　要：纤细裸藻是我国于2013年批准的新资源食品,纤细裸藻具有极高的营养价值,含有氨基酸组成合理的蛋白质、具有特殊生理功效的β-1,3-葡聚糖三螺旋晶体、维生素E中活性最强的同分异构体α-生育酚、多不饱和脂肪酸、矿物质等。该文首先从纤细裸藻异养发酵条件因子优化与培养基质代谢机制两个方面研究进行归纳;其次对裸藻β-1,3-葡聚糖的发酵制备、纯化、结构分析等进行了介绍;最后从促进免疫力、抗病毒、抑制肿瘤等方面归纳了裸藻β-1,3-葡聚糖生理功效方面的研究进展。旨在为裸藻异养发酵的应用研究与基质代谢基础研究提供理论支持;为裸藻β-1,3-葡聚糖在食品、药物、化妆品、新材料等领域的开发应用提供支持。Euglena gracilis is the new resource food approved by China in 2013.It has high nutritional value and contains proteins with reasonable amino acid composition,β-1,3-glucans triple helix crystal with special physiological functions,α-tocopherol with the most active in isomer of vitamin E,polyunsaturated fatty acids,minerals and so on.Firstly,the optimization of heterotrophic fermentation conditions and the metabolic mechanism of culture substrate ofE.gracilis were summarized.Secondly,the fermentation preparation,purification and structure analysis ofE.gracilisβ-1,3-glucan were introduced.In the end,the research progress on physiological effects of E.gracilisβ-1,3-glucan was summarized from the aspects of immunity enhancement,antiviral,tumor inhibition and so on.This review provided theoritical support for the application research of heterotrophic fermentation and basic research of substrate metabolism of E.gracilis,and provided support for the the development and application of E.gracilisβ-1,3-glucan in food,medicine,cosmetics,new materials and other fields.

关 键 词：纤细裸藻 β-1 3-葡聚糖 异养发酵 生理功效 

分 类 号：TS245.9[轻工技术与工程—制糖工程]