基于事件相关电位的中西医命题认知差异研究  

Cognitive Difference of Traditional Chinese and Western Medicine Propositions:An Event Related Potential Study

作　　者：窦嘉乐 黄慧雯 吴彤 刘庆华 贾春华 李鹏英 刘丹彤 DOU Jiale;HUANG Huiwen;WU Tong;LIU Qinghua;JIA Chunhua;LI Pengying;LIU Dantong(School of Traditional Chinese Medicine,Beijing University of Chinese Medicine,Beijing 100029,China;School of Basic Medicine,Zhejiang Chinese Medical University,Hangzhou 310053,China;School of Basic Medical Sciences,Shaanxi University of Chinese Medicine,Xianyang 712046,China)

机构地区：[1]北京中医药大学中医学院,北京100029 [2]浙江中医药大学基础医学院,杭州310053 [3]陕西中医药大学基础医学院,咸阳712046

出　　处：《世界中医药》2022年第23期3308-3312,共5页World Chinese Medicine

基　　金：国家自然科学基金项目(81874514)——基于事件相关电位与功能性磁共振成像技术的中医语言研究;国家自然科学基金项目(82074582)——中医五行推理的逻辑解析与ERP及fMRI的实证研究。

摘　　要：目的:应用事件相关电位技术,捕捉大脑判断中、西医命题时产生的脑电成分,探索不同医学命题理解过程的脑神经机制,为中西医的思维差异提供认知神经科学层面的研究证据。方法:采用尾词范式与句义正确性判断任务,采集中医相关专业研究生在理解中医、西医命题时产生的脑电数据。应用重复测量方差分析对早期左前负成分(ELAN)、200 ms事件相关电位正波(P200)、400 ms事件相关电位负波(N400)、600 ms事件相关电位正波(P600)时间窗的结果数据进行统计。结果:在ELAN、P200时间窗,中西医命题的波幅差异不显著(P>0.05);在N400时间窗,西医命题比中医命题诱发了更负的波幅(P=0.04);在P600时间窗,中医命题比西医命题诱发了更正的波幅(P=0.01)。结论:在命题加工的前期词汇识别阶段,西医命题比中医存在更显著的具体性效应;在后期语义整合阶段,中医命题比西医涉及更多的整合加工,可能反映了中医语言的隐喻映射加工进程。Objective:To capture the EEG components generated by the brain in judging traditional Chinese and western medicine propositions using event related potential(ERP)technique,explore the brain neural mechanism in understanding different medical propositions,and provide evidence for studying the thinking difference between traditional Chinese and western medicine at the cognitive neuroscience level.Methods:The EEG data of students majoring in traditional Chinese medicine(TCM)in understanding traditional Chinese and western medicine propositions were collected by suffix paradigm and sentence correctness judgment task.Repeated measures ANOVA was used to analyze the early left anterior negativity(ELAN),P200,N400 and P600 time windows.Results:In ELAN and P200 time windows,there was no significant difference between the amplitudes of traditional Chinese and western medicine propositions(P>0.05).In N400 time window,western medicine propositions induced more negative amplitudes than TCM propositions(P=0.04).In P600 time window,TCM propositions elicited more positive amplitudes(P=0.01)than western medicine propositions.Conclusion:In the early stage of word recognition in proposition processing,western medicine propositions have more specific effect than TCM propositions.In the later stage of semantic integration,TCM propositions involve more integration processing than western medicine propositions.These may reflect the metaphorical mapping of TCM language.

关 键 词：中医语言 西医语言 命题 思维差异 隐喻认知 事件相关电位 400 ms事件相关电位负波 600 ms事件相关电位正波 

分 类 号：R2-03[医药卫生—中医学]