并发糖尿病、足溃疡及性腺功能减退Werner综合征三例报道  

Werner syndrome with diabetes mellitus, foot ulcers, and hypogonadism: three cases report

作　　者：袁晶晶[1] 何红晖[1] 熊静[1] 赵少俐[1] 谢艳红[1] 陈科[1] 金萍[1] 莫朝晖[1] YUAN Jingjing;HE Honghui;XIONG Jing(Department of Endocrinology,TheThird Xiangya Hospital of Centre South University,Changsha 410013,China)

机构地区：[1]中南大学湘雅三医院内分泌科,长沙410013

出　　处：《中国糖尿病杂志》2022年第11期859-865,共7页Chinese Journal of Diabetes

基　　金：北京泰德TRUST基金(KY080278)。

摘　　要：Werner综合征(WS)是常染色体隐性遗传病,是成人发病的早老综合征,总发病率为1:100万~1000万。本报告分析3例并发DM、足溃疡及性腺功能减退WS患者临床特征、实验室和影像学检查,完善相关基因检测。Werner syndrome(WS)is an autosomal recessive disease. It is an adult onset early aging syndrome with a total incidence rate of 1:1 million to 1:10 million. In this report,we described the clinical features,laboratory and imaging examinations of 3 cases of WS complicated with diabetes mellitus,foot ulcer and hypogonadism,and also the relevant gene testing.

关 键 词：糖尿病 WERNER综合征 基因突变 

分 类 号：R587.2[医药卫生—内分泌] R596[医药卫生—内科学]