Wilhelmy吊片法测定磷脂溶液的表面张力等温线  

Determination of Surface Tension Isotherm of Phospholipid Solution Using Wilhelmy Method

作　　者：李远非 杨训方 王桂玲[1] 郭莹[1] 王煦[1] 李馨儒[1] 周艳霞[1] 谢英[1] Yuanfei Li;Xunfang Yang;Guiling Wang;Ying Guo;Xu Wang;Xinru Li;Yanxia Zhou;Ying Xie(School of Pharmaceutical Sciences,Peking University,Beijing 100191,China)

机构地区：[1]北京大学药学院,北京100191

出　　处：《大学化学》2023年第1期155-160,共6页University Chemistry

基　　金：北京大学2020年本科教育教学改革项目(202010892-01)。

摘　　要：表面活性物质的表面张力等温线测定是大学物理化学实验的重要内容。随着磷脂类表面活性剂的广泛应用,有必要在大学化学中更新经典表面张力等温线测定的实验内容,并使学生掌握先进的测量方法。以二硬脂酰基磷脂酰胆碱(DSPC)和二棕榈酰基磷脂酰胆碱(DPPC)为研究对象,应用界面张力仪测定了两种溶液表面张力等温线,计算了其表面超量和分子横截面积,并设计了拓展性实验内容,对于培养学生分析问题和解决问题的能力具有积极的意义。The determination of surface tension isotherm of surfactants is an important experiment of college physical chemistry laboratory.With the wide application of surfactants and the development of scientific instruments,it is necessary to update the experimental system of classical surface tension isotherm measurements.Herein,the surface tension isotherm of distearoyl phosphatidylcholine(DSPC)and dipalmitoyl phosphatidylcholine(DPPC)were determined by interfacial tensiometer,and the important parameters such as surface excess and cross-sectional area of molecules were calculated.An extended experiment was also suggested so as to promote the students’comprehensive knowledge and cultivate the students’ability to analyze and solve problems.

关 键 词：磷脂 表面张力等温线 实验教学 

分 类 号：G642.0[文化科学—高等教育学] O647.2[文化科学—教育学]