运动锻炼对毒品成瘾者渴求度影响的Meta分析  

Effect of exercise on craving of drug addicts:a meta-analysis of randomized controlled study

作　　者：张泽平 汪晓丽 南洋 徐定 杨苏勇 ZHANG Ze-ping;WANG Xiao-li;NAN Yang;XU Ding;YANG Su-yong(School of Wushu,Shanghai University of Sport,Shanghai 200438,China;School of Leisure Sport,Shanghai University of Sport,Shanghai 200438,China;Shanghai Drug Rehabilitation Administration,Shanghai 200438,China;School of Psychology,Shanghai University of Sport,Shanghai 200438,China)

机构地区：[1]上海体育学院武术学院,上海200438 [2]上海体育学院休闲学院,上海200438 [3]上海市戒毒管理局,上海200080 [4]上海体育学院心理学院,上海200438

出　　处：《中国药物依赖性杂志》2022年第5期380-385,共6页Chinese Journal of Drug Dependence

基　　金：上海戒毒管理局项目(SF201920107)。

摘　　要：目的系统评价运动锻炼对毒品成瘾者渴求度的影响。方法检索PubMed、Embase、EBSCOhost、Web of Science、WanFang Data和CNKI数据库,收集有关运动锻炼对毒品成瘾者渴求度影响的随机对照研究,由2名研究人员根据文献纳入标准独立筛选文献、提取资料与纳入文献方法学质量评价,采用RevMan 5.3和Stata14.0软件进行Meta分析。结果最终纳入10篇文献,包括606例患者。Meta分析结果显示运动干预效应显著,即运动锻炼组的毒品渴求度显著低于[SMD=-0.57,95%CI(-0.80,-0.33),P<0.01]常规康复组。亚组分析结果显示:在男性被试、吸毒时间5年以上、有氧运动等亚组中有显著的运动干预效应;训练时间在30~50 min和60~90 min、运动频率在每周3次和每周3次以上、运动周期在4~8周和12~24周等亚组中均有显著的运动干预效应。结论当前证据表明,与常规康复相比,运动锻炼对毒品成瘾者的戒毒康复有明显改善作用。尽管部分结果提示,性别、吸毒时间和运动方式可能是影响运动干预效应的重要因素,但有待更多的研究证据支持。Objective To systematically review the efficacy of exercise on the craving of drug addicts.Methods PubMed,Embase,EBSCOhost,Web of Science,WanFang Data,and CNKI databases were electronically searched to collect randomized controlled trials(RCTs)on the effects of exercise on cravings in drug addicts.Two researchers independently screened the literature according to the inclusion criteria,extracted the data,and evaluated the methodological quality of the included studies.Then,RevMan5.3 and Stata14.0 software were used for meta-analysis.Results A total of 10 articles were included with 606 patients.The results of the meta-analysis showed that the drug craving of the exercise group was significantly lower than that of the conventional rehabilitation group(SMD=-0.57,95%CI-0.80 to-0.33,P<0.01).The subgroup analysis showed that there were significant effects of exercise intervention in male subjects,drug use time for more than 5 years and aerobic exercise subgroup.There was a significant effect of exercise intervention in both the subgroup of exercise time of 30~50 min and that of 60~90 min,of exercise frequency of 3 times a week and that of more than 3 times a week,of exercise cycle of 4~8 weeks and that of 12~24 weeks.Conclusions The present evidence shows that physical exercise can significantly improve the rehabilitation effect of drug addicts compared with conventional rehabilitation.Although some of the results suggest that gender,time of drug abuse,and exercise mode may be the important factors of the exercise intervention effects,more research evidence is needed.

关 键 词：运动锻炼 有氧运动 抗阻训练 渴求度 毒品成瘾者 META分析 

分 类 号：R749[医药卫生—神经病学与精神病学]