Immune and metabolic cross-links in the pathogenesis of comorbid non-alcoholic fatty liver disease  

作　　者：Stanislav Kotlyarov 

机构地区：[1]Department of Nursing,Ryazan State Medical University,Ryazan 390026,Russia

出　　处：《World Journal of Gastroenterology》2023年第4期597-615,共19页世界胃肠病学杂志（英文版）

摘　　要：In recent years,there has been a steady growth of interest in non-alcoholic fatty liver disease(NAFLD),which is associated with negative epidemiological data on the prevalence of the disease and its clinical significance.NAFLD is closely related to the metabolic syndrome and these relationships are the subject of active research.A growing body of evidence shows cross-linkages between metabolic abnormalities and the innate immune system in the development and progression of NAFLD.These links are bidirectional and largely still unclear,but a better understanding of them will improve the quality of diagnosis and management of patients.In addition,lipid metabolic disorders and the innate immune system link NAFLD with other diseases,such as atherosclerosis,which is of great clinical importance.

关 键 词：Non-alcoholic fatty liver disease Metabolism Lipid metabolism LIPID FAT Innate immune system PATHOGENESIS 

分 类 号：R575.5[医药卫生—消化系统]