复合燕麦高纤维杂粮粉对高脂饮食诱导的小鼠肥胖的干预作用  

Intervention Effect of Oat High-fiber Multi-grain Powder on Obesity Induced by High-fat Diet in Mice

作　　者：霍瑞 张美莉[1] 张亚琨[1] Huo Rui;Zhang Meili;Zhang Yakun(College of Food Science and Engineering,Inner Mongolia Agricultural University,Hohhot 010018)

机构地区：[1]内蒙古农业大学食品科学与工程学院,呼和浩特010018

出　　处：《中国食品学报》2023年第5期105-112,共8页Journal of Chinese Institute Of Food Science and Technology

基　　金：内蒙古自治区科技重大专项(2021ZD0002)。

摘　　要：以燕麦-玉米-魔芋挤压膨化混粉、燕麦麸皮微粉、脱脂乳粉、葛根全粉、南瓜粉为基础原料,制备一种高膳食纤维粉,探究其对高脂饮食小鼠的肥胖干预效果。小鼠适应性喂养7 d后分为空白组、高脂饮食组、实验组、阳性组,灌胃8周后观察并测定小鼠体质量、血糖、脂代谢水平并做组织切片。结果表明,与高脂饮食组相比,高纤维饮食干预能显著降低小鼠的体质量、腹部脂肪质量和空腹血糖值(P<0.05);吸附血液和肝脏中的胆固醇,肝脏胆固醇和甘油三酯含量相比高脂饮食组分别降低45.63%和41.98%;减少高脂饮食引起的肝脏损伤,显著提升血清中高密度脂蛋白含量(P<0.05),降低低密度脂蛋白、谷草转氨酶和谷丙转氨酶含量。该膳食纤维粉可以减轻小鼠体质量,改善脂代谢和肥胖引起的肝脏损伤。Using oat-corn-konjac extruded powder,oat bran powder,skimmed milk powder,kudzu root powder,pumpkin powder as basic raw materials,prepared a high dietary fiber powder and explored the effect of obesity intervention on high-fat diet mice.Mice were adaptively fed for 7 days and were divided into blank group,high-fat diet group,experimental group,positive group.After 8 weeks of intragastric administration,the weight,blood glucose,lipid metabolism and tissue sections of the mice were observed and measured.The results showed that compared with the high-fat diet group,high fiber diet could significantly reduce the body weight,abdominal fat weight and fasting blood glucose value of mice(P<0.05);it could absorb cholesterol,cholesterol and triglyceride content in blood and liver.Compared with the high-fat diet group,liver cholesterol and triglyceride content was reduced by 45.63%and 41.98%,respectively.The meal replacement powder intervention also reduced liver damage caused by high-fat diet,significantly increased serum high-density lipoprotein(P<0.05),and reduced low-density lipoprotein,aspartate aminotransferase and alanine aminotransferase content.The formula powder in this study can reduce the weight of mice and improve liver damage caused by fat metabolism and obesity.

关 键 词：杂粮 膳食纤维 肥胖 脂质代谢 

分 类 号：TS201.4[轻工技术与工程—食品科学]