叶黄素咀嚼片中功效成分含量测定方法学验证试验设计  

Method Validation Experimental Design for the Determination of Functional Ingredient in Lutein Chewable Tablets

作　　者：张莉华 吕红萍 陈少军 王胜南 刘爱琴 许新德 ZHANG Lihua;LüHongping;CHEN Shaojun;WANG Shengnan;LIU Aiqin;XU Xinde(Zhejiang Pharmaceutical University,Ningbo 315100;Zhejiang Keming Biopharmaceuticals Co.,Ltd.,Xinchang 312500;Xinchang Pharmaceutical Factory of Zhejiang Medicine Co.,Ltd.,Xinchang 312500)

机构地区：[1]浙江药科职业大学,宁波315100 [2]浙江可明生物医药有限公司,新昌312500 [3]浙江医药股份有限公司新昌制药厂,新昌312500

出　　处：《食品工业》2023年第6期133-137,共5页The Food Industry

摘　　要：为培养学生的实践和应用能力,设计叶黄素咀嚼片中功效成分含量测定方法学验证综合试验。采用紫外-可见分光光度法测定叶黄素咀嚼片中的叶黄素含量,进行专属性、线性、精密度、准确度、稳定性等指标的方法学考察,为叶黄素咀嚼片质量控制和功效成分含量的测定奠定基础。试验不仅让学生掌握方法学验证的思路、内容和过程,而且训练学生综合运用所学知识解决实际问题的能力,在实践中交流合作,科学探索。To cultivate students' practice and application ability,a comprehensive experiment of method validation for the determination of the content of functional component in lutein chewable tablets was designed.The UV-vis spectrophotometry was performed for determination of lutein content in lutein chewable tables.Method validation included exclusivity,linearity,precision,accuracy and stability,which laid the foundation for the control the quality and assay the content of functional ingredient in lutein chewable tablets.The comprehensive experiment not only enables students to master the idea,content and process of method validation,but also strengthens the students' ability to apply their knowledge to solve practical problems.In addition,it is helpful to cultivate students' spirit of cooperation and scientific inquiry.

关 键 词：含量测定 叶黄素 方法学验证 试验设计 

分 类 号：G642.423[文化科学—高等教育学] TS218-4[文化科学—教育学]