Cancer stem cells in drug resistance:an introduction to the e-book covering the special issue on the“Cancer Stem Cells and Drug Resistance”  

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作  者:Balázs Sarkadi 

机构地区:[1]Institute of Enzymology,Research Centre for Natural Sciences,Budapest 1117,Hungary

出  处:《Cancer Drug Resistance》2023年第2期239-241,共3页癌症耐药(英文)

摘  要:A major problem in current cancer drug treatment is that a subset of cancer cells in many cases survives even highly efficient chemotherapy,and after a while,these remaining cells cause a recurrence of the disease.Moreover,the re-emerging cancer cells often show a multidrug-resistant phenotype,higher proliferation rate,higher invasiveness,and increased metastatic potential,as compared to original cancer.Cancer relapse and multidrug resistance are widely observed also in the most up-to-date,specifically targeted drug-or immunotherapies,causing an unsurmountable clinical inefficiency in cancer eradication.

关 键 词:CANCER DRUG CANCER 

分 类 号:R73-5[医药卫生—肿瘤] G23[医药卫生—临床医学]

 

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