癫痫猝死的危险因素与风险评估研究进展  

The research advance of risk factors and risk assessment of sudden unexpected death in epilepsy

作　　者：曾裕豪 卓雯 洪葵[1] Zeng Yuhao;Zhuo Wen;Hong Kui(Department of Cardiology,the Second Affiliated Hospital of Nanchang University,Nanchang 330006,China)

机构地区：[1]南昌大学第二附属医院心内科,南昌330006

出　　处：《中华神经科杂志》2023年第7期837-841,共5页Chinese Journal of Neurology

基　　金：江西省科技支撑项目(20203AEI005)。

摘　　要：癫痫是一类常见的神经系统疾病,患者常表现出不可预测的自发性癫痫发作。癫痫猝死是癫痫最为严重的并发症之一,也是癫痫患者过早死亡的主要原因。全身性强直阵挛发作、年龄及遗传等均为癫痫猝死的常见危险因素。文中就癫痫的流行病学、致病机制、危险因素、风险评估和预防对癫痫猝死进行综述,以帮助临床医生更好地区分癫痫猝死与心脏猝死。Epilepsy is a common disease in nervous system,of which patients often present with spontaneous unpredictable spontaneous seizures.Sudden unexpected death in epilepsy(SUDEP)is one of the most serious complications of epilepsy,and it is also the main cause of premature death of epileptic patients.Generalized tonic-clonic seizures,age and genetic factors are common risk factors of SUDEP.This article summarizes the classification of SUDEP and epidemiology,mechanism,risk factors,risk assessment and preventive methods of SUDEP to help physicians to understand the difference between SUDEP and sudden cardiac death.

关 键 词：癫痫猝死 危险因素 风险评估 致病基因 

分 类 号：R742.1[医药卫生—神经病学与精神病学]