牡丹花粉片糖配方优化及其消化产物的体外抗氧化活性评价  

Optimization of the Formula Process of the Peony Pollen Candy in Tablet and Evaluation of in Vitro Antioxidant Activity of Various Digestive Products

作　　者：范彬[1] 彭腾腾 王信 沈薇[1] 马趣环[1] 王新娣[1] 刘东彦[1] 尹盼盼 李海燕 石晓峰[1] FAN Bin;PENG Tengteng;WANG Xin;SHEN Wei;MA Quhuan;WANG Xindi;LIU Dongyan;YIN Panpan;LI Haiyan;SHI Xiaofeng(Gansu Academy of Medical Science,Lanzhou 730050,China;School of Pharmacy,Gansu College of TCM,Lanzhou 730000,China)

机构地区：[1]甘肃省医学科学研究院,甘肃兰州730050 [2]甘肃中医药大学药学院,甘肃兰州730000

出　　处：《食品工业科技》2023年第15期258-263,共6页Science and Technology of Food Industry

基　　金：兰州市人才创新创业项目(2021-RC-112);兰州市科学技术局项目(2020-XG-21);兰州市科技发展指导性计划项目(2019-ZD-132);甘肃省省级中医药科研课题(GZK-2017-44)。

摘　　要：目的:优选牡丹花粉片糖的配方工艺,并评价其体外抗氧化活性。方法:通过单因素实验对牡丹花粉片糖配方进行遴选;以牡丹花粉、填充剂和甜味剂用量为考察因素,以牡丹花粉片糖的感官指标、硬度、崩解时限的综合评分为评价指标,利用响应面法对牡丹花粉片糖的配方进行优化,并测定其模拟人体各消化产物对DPPH和ABTS+自由基的清除能力。结果:优选出牡丹花粉片糖的最佳配方为牡丹花粉0.7 g,填充剂3.3 g,甜味剂1.7 g,该配方工艺的综合评分为6.39。模拟人体累加消化产物对DPPH和ABTS+自由基最高清除率为91.56%和96.42%。结论:该牡丹花粉片糖配方工艺简便,易于操作,保留了花粉的特有风味,具有体外抗氧化活性。Objective:To optimize the formula process of peony pollen candy in tablets and evaluate its antioxidant activity in vitro.Methods:On the basis of the single-factor experiment,taking the dosage of peony pollen,filler,and sweetener as factors,applying the comprehensive scores of the sensory,hardness,and disintegration time as evaluation indexes,the formula process of the peony pollen candy in tablets was optimized by response surface methodology.The DPPH and ABTS+free radical scavenging capacity of various digestive products of the peony pollen candy in tablets simulated in the human body were determined.Results:The optimal prescription of the candy was as follows:0.7 g of peony pollen,3.3 g of the filler,and 1.7 g of the sweetener.The comprehensive score of this formula process was 6.39.The maxima scavenging rates of DPPH and ABTS+free radicals by accumulated digestive products simulated in the human body were 91.56%and 96.42%,respectively.Conclusion:The formula of the peony pollen candy in tablets is simple and easy to handle.It retains the unique flavor of the peony pollen and maintains in vitro antioxidant activity.

关 键 词：牡丹花粉 片糖 配方优化 响应面分析 抗氧化性 

分 类 号：TS201.2[轻工技术与工程—食品科学]