新型溶栓制剂——纳豆激酶的研究进展  

Research progress of Nattokinase as a new thrombolytic agent

作　　者：刘梦璐 李宁 高学秀 袁卫涛 曹建帮 李成顺 李静 陈又铭 LIU Menglu;LI Ning;GAO Xuexiu;YUAN Weitao;CAO Jianbang;LI Chengshun;LI Jing;CHEN Youming(Shandong Starlight So True Biological Technology Co.,Ltd.,Dezhou 253600)

机构地区：[1]山东星光首创生物科技有限公司,德州253600

出　　处：《中国食品添加剂》2023年第11期277-284,共8页China Food Additives

摘　　要：现代社会中,血栓威胁着人类的健康。现有的溶栓药物中,纤溶酶对溶栓具有显著效果。与其他微生物纤溶酶相比,纳豆激酶具有成本低、作用时间长、副作用少等优点,具有作为缓解心血管疾病功能性食品和药物的潜力。本综述旨在详细介绍纳豆激酶相关性质、生理功效、制备工艺的最新进展,以及应用面临的挑战和前景,以期为纳豆激酶的综合开发利用提供理论依据。In modern society,thrombosis threatens human health.Among the existing thrombolytic drugs,plasmin has a significant effect on thrombolysis.Compared with other microbial plasmin,nattokinase has the advantages of low cost,long action time,and few side effects,it has the potential to be used as a functional food and drug for relieving and preventing cardiovascular disease.This review aimed to introduce the latest progress in detail of nattokinase properties,physiological efficacy,preparation technology,as well as the challenges and prospects of its applications in order to provide a theoretical basis for the comprehensive development and utilization of nattokinase.

关 键 词：溶栓制剂 纳豆激酶 生理功效 制备工艺 

分 类 号：TS202.1[轻工技术与工程—食品科学]